PreprintAll rights reservedbioRxiv23 Sep 2026

Constitutive PI3K-AKT activation promotes steatohepatitis through de novo lipogenesis despite enhanced mitochondrial β-oxidation, essential fatty acid depletion and reduced lipid peroxidation

A. S. Peixoto
E. Castro
B. F. Leonardi
T. E. Oliveira
A. B. Chaves-Filho
T. S. Vieira
C. A. Tomazelli
N. M. Pessoa
E. V. M. Pessoa
M. A. Abe-Honda
A. B. Pires
L. P. Silva Junior

7 more authors

E. M. Silveira
B. P. Silva
C. N. Bezerra
F. C. Meotti
M. Y. Yoshinaga
S. Miyamoto
W. T. Festuccia¹

¹Institute of Biomedical Sciences, University of Sao Paulo

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BibTeX

@misc{peixoto2026constitutive,
  title = {{Constitutive PI3K-AKT activation promotes steatohepatitis through de novo lipogenesis despite enhanced mitochondrial β-oxidation, essential fatty acid depletion and reduced lipid peroxidation}},
  author = {A. S. Peixoto and E. Castro and B. F. Leonardi and T. E. Oliveira and A. B. Chaves-Filho and T. S. Vieira and C. A. Tomazelli and N. M. Pessoa and E. V. M. Pessoa and M. A. Abe-Honda and A. B. Pires and L. P. Silva Junior and E. M. Silveira and B. P. Silva and C. N. Bezerra and F. C. Meotti and M. Y. Yoshinaga and S. Miyamoto and W. T. Festuccia},
  howpublished = {bioRxiv},
  year = {2026},
  month = sep,
  doi = {10.64898/2026.09.23.753762},
  url = {https://www.biorxiv.org/content/10.64898/2026.09.23.753762v1},
}

RIS

TY  - UNPB
TI  - Constitutive PI3K-AKT activation promotes steatohepatitis through de novo lipogenesis despite enhanced mitochondrial β-oxidation, essential fatty acid depletion and reduced lipid peroxidation
AU  - A. S. Peixoto
AU  - E. Castro
AU  - B. F. Leonardi
AU  - T. E. Oliveira
AU  - A. B. Chaves-Filho
AU  - T. S. Vieira
AU  - C. A. Tomazelli
AU  - N. M. Pessoa
AU  - E. V. M. Pessoa
AU  - M. A. Abe-Honda
AU  - A. B. Pires
AU  - L. P. Silva Junior
AU  - E. M. Silveira
AU  - B. P. Silva
AU  - C. N. Bezerra
AU  - F. C. Meotti
AU  - M. Y. Yoshinaga
AU  - S. Miyamoto
AU  - W. T. Festuccia
PY  - 2026
DA  - 2026/09/23
PB  - bioRxiv
DO  - 10.64898/2026.09.23.753762
UR  - https://www.biorxiv.org/content/10.64898/2026.09.23.753762v1
ER  -

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