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Peer-reviewedCC BYJournal of cardiothoracic surgery

B‑lines on lung ultrasound: a non‑invasive marker for short‑term outcomes after coronary artery bypass grafting.

5 affiliations
  1. 1Department of Anesthesilogy, Dr Ali Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
  2. 2Tehran University of Medical Sciences, Tehran, Iran.
  3. 3Department of Neurology, Dr Rajaee Hospital, Alborz University of Medical Sciences, Alborz, Iran.
  4. 4Shariati Hospital, Cardiovascular Surgical ICU, Tehran University of Medical Sciences, Tehran, Iran.
  5. 5Department of Anesthesilogy, Dr Ali Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. [email protected].

Abstract

Background

Postoperative pulmonary complications increase morbidity and mortality after coronary artery bypass grafting (CABG). Lung ultrasound detection of B-lines is an established method to quantify pulmonary congestion, and while B-lines have been studied as predictive markers in heart failure and general critical care settings, their role in predicting outcomes specifically for post-CABG patients remains inadequately defined. This study aimed to evaluate the association between B-lines detected on postoperative lung ultrasound and 30-day mortality and hospital length of stay in patients undergoing isolated CABG.Methods

This prospective cohort study was conducted in a single-center intensive care unit between 2023 and 2024. A total of 148 adult patients scheduled for elective CABG were enrolled. Lung ultrasound was performed on postoperative days 1 (POD1) and 3 (POD3) using a standardized 8-zone protocol to quantify B-lines. The primary outcomes were all-cause 30-day mortality, assessed via hospital records and telephone follow-up, and total hospital length of stay. Univariate and multivariate logistic and linear regression analyses were used to identify predictors.Results

The mean patient age was 60.15 ± 9.8 years, and 57% were male. Within 30 days, 22 patients (15%) died. In the multivariate logistic regression, the number of B-lines on POD1 was an independent predictor of 30-day mortality (Adjusted Odds Ratio: 1.090, 95% CI: 1.018-1.167, p = 0.013), indicating a 9% increase in the odds of death for each additional B-line. In contrast, the B-line count on POD3 was not significantly associated with mortality. B-line counts on both days were also not associated with hospital length of stay. Instead, higher body mass index (β = 0.22, p = 0.022) and a history of smoking (β = 2.20, p = 0.020) were independently associated with longer hospitalization.Conclusions

Early postoperative pulmonary congestion, as quantified by B-lines on POD1 lung ultrasound, is an independent predictor of 30-day mortality after CABG. Routine bedside lung ultrasound on the first day after surgery can serve as a non-invasive tool to stratify high-risk patients, potentially allowing for earlier intervention to optimize fluid status and improve outcomes.

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BibTeX
@article{afrakoti2026blines,
  title = {{B‑lines on lung ultrasound: a non‑invasive marker for short‑term outcomes after coronary artery bypass grafting.}},
  author = {Nima Mohamadi Afrakoti and Mahan Khani and Sina Hemmati and Ali Ebrahiminasab and Reza Atef Yekta and Samaneh Hajy Molla Rabi and Elham Pagard and Mojtaba Marashi},
  journal = {Journal of cardiothoracic surgery},
  year = {2026},
  month = aug,
  doi = {10.1186/s13019-026-04573-0},
  url = {https://europepmc.org/article/MED/42958410},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - B‑lines on lung ultrasound: a non‑invasive marker for short‑term outcomes after coronary artery bypass grafting.
AU  - Nima Mohamadi Afrakoti
AU  - Mahan Khani
AU  - Sina Hemmati
AU  - Ali Ebrahiminasab
AU  - Reza Atef Yekta
AU  - Samaneh Hajy Molla Rabi
AU  - Elham Pagard
AU  - Mojtaba Marashi
PY  - 2026
DA  - 2026/08/01
JO  - Journal of cardiothoracic surgery
DO  - 10.1186/s13019-026-04573-0
UR  - https://europepmc.org/article/MED/42958410
AB  - Background  Postoperative pulmonary complications increase morbidity and mortality after coronary artery bypass grafting (CABG). Lung ultrasound detection of B-lines is an established method to quantify pulmonary congestion, and while B-lines have been studied as predictive markers in heart failure and general critical care settings, their role in predicting outcomes specifically for post-CABG patients remains inadequately defined. This study aimed to evaluate the association between B-lines detected on postoperative lung ultrasound and 30-day mortality and hospital length of stay in patients undergoing isolated CABG.Methods  This prospective cohort study was conducted in a single-center intensive care unit between 2023 and 2024. A total of 148 adult patients scheduled for elective CABG were enrolled. Lung ultrasound was performed on postoperative days 1 (POD1) and 3 (POD3) using a standardized 8-zone protocol to quantify B-lines. The primary outcomes were all-cause 30-day mortality, assessed via hospital records and telephone follow-up, and total hospital length of stay. Univariate and multivariate logistic and linear regression analyses were used to identify predictors.Results  The mean patient age was 60.15 ± 9.8 years, and 57% were male. Within 30 days, 22 patients (15%) died. In the multivariate logistic regression, the number of B-lines on POD1 was an independent predictor of 30-day mortality (Adjusted Odds Ratio: 1.090, 95% CI: 1.018-1.167, p = 0.013), indicating a 9% increase in the odds of death for each additional B-line. In contrast, the B-line count on POD3 was not significantly associated with mortality. B-line counts on both days were also not associated with hospital length of stay. Instead, higher body mass index (β = 0.22, p = 0.022) and a history of smoking (β = 2.20, p = 0.020) were independently associated with longer hospitalization.Conclusions  Early postoperative pulmonary congestion, as quantified by B-lines on POD1 lung ultrasound, is an independent predictor of 30-day mortality after CABG. Routine bedside lung ultrasound on the first day after surgery can serve as a non-invasive tool to stratify high-risk patients, potentially allowing for earlier intervention to optimize fluid status and improve outcomes.
SN  - 1749-8090
ER  -