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Peer-reviewedCC BY 4.0Nucleic Acids Research

GlyTouCan v4: a redesigned interface and expanded functionality for the international glycan structure repository

  • Masaaki Shiota1
  • Tamiko Ono1
  • Masaaki Matsubara2
  • Naoki Kimura2
  • Thomas Masding3
  • Nobuki Tsukada3
  • Kazuya Inoue3
  • Issaku Yamada2
  • Kiyoko F Aoki-Kinoshita1,3
  1. 1Glycan and Life Systems Integration Center, Soka University , 1-236 Tangi-machi, Hachioji-shi, Tokyo 192-8577 ,
  2. 2The Noguchi Institute , 1-9-7 Kaga, Itabashi, Tokyo 173-0003 ,
  3. 3Graduate School of Science and Engineering, Soka University , 1-236 Tangi-machi, Hachioji-shi, Tokyo 192-8577 ,
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Abstract

GlyTouCan (https://glytoucan.org) is the international, species-neutral glycan structure repository that assigns stable, globally unique accession numbers to glycan structures independently of the experimental method used to determine them. Here, we describe GlyTouCan version 4, released on June 22, 2026, which introduces a completely redesigned user interface with substantially faster browsing and searching, including a new “archetype” view that groups registrations that differ only in the anomeric or ring form of the reducing-end residue together for clearer filtering of the >256,000 glycans now registered. Version 4 provides an improved graphical structure input, via the updated browser-embedded GlycanBuilder application, for both searching and registering structures. Users may now sign in with an ORCID ID in addition to a Google account, and all previously released v3 REST API endpoints remain fully backward compatible. Version 4 also introduces a framework for industry affiliates, providing a structured pathway for commercial organizations that work with or synthesize glycans, while all existing academic database-partner relationships are maintained. GlyTouCan remains freely available to all users without charge, login, or registration for browsing and searching. We also summarize the repository’s data content, which spans >600 monosaccharide types and, judging from these, includes many glycans of probable bacterial or plant origin.

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Cite

BibTeXRIS
BibTeX
@article{shiota2026glytoucan,
  title = {{GlyTouCan v4: a redesigned interface and expanded functionality for the international glycan structure repository}},
  author = {Masaaki Shiota and Tamiko Ono and Masaaki Matsubara and Naoki Kimura and Thomas Masding and Nobuki Tsukada and Kazuya Inoue and Issaku Yamada and Kiyoko F Aoki-Kinoshita},
  journal = {Nucleic Acids Research},
  year = {2026},
  month = nov,
  doi = {10.1093/nar/gkag1119},
  url = {https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkag1119/9013042},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - GlyTouCan v4: a redesigned interface and expanded functionality for the international glycan structure repository
AU  - Masaaki Shiota
AU  - Tamiko Ono
AU  - Masaaki Matsubara
AU  - Naoki Kimura
AU  - Thomas Masding
AU  - Nobuki Tsukada
AU  - Kazuya Inoue
AU  - Issaku Yamada
AU  - Kiyoko F Aoki-Kinoshita
PY  - 2026
DA  - 2026/11/05
JO  - Nucleic Acids Research
DO  - 10.1093/nar/gkag1119
UR  - https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkag1119/9013042
AB  - GlyTouCan (https://glytoucan.org) is the international, species-neutral glycan structure repository that assigns stable, globally unique accession numbers to glycan structures independently of the experimental method used to determine them. Here, we describe GlyTouCan version 4, released on June 22, 2026, which introduces a completely redesigned user interface with substantially faster browsing and searching, including a new “archetype” view that groups registrations that differ only in the anomeric or ring form of the reducing-end residue together for clearer filtering of the >256,000 glycans now registered. Version 4 provides an improved graphical structure input, via the updated browser-embedded GlycanBuilder application, for both searching and registering structures. Users may now sign in with an ORCID ID in addition to a Google account, and all previously released v3 REST API endpoints remain fully backward compatible. Version 4 also introduces a framework for industry affiliates, providing a structured pathway for commercial organizations that work with or synthesize glycans, while all existing academic database-partner relationships are maintained. GlyTouCan remains freely available to all users without charge, login, or registration for browsing and searching. We also summarize the repository’s data content, which spans >600 monosaccharide types and, judging from these, includes many glycans of probable bacterial or plant origin.
SN  - 0305-1048
SN  - 1362-4962
ER  -