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Peer-reviewedCC BY 4.0Journal of Medical Primatology

Cynomolgus Monkey (Macaca fascicularis) Embryo Models: From Developmental Benchmarks to Functionally Testable Embryoids

  • Yeojeong Jeong1,2
  • Jongwon Byun2,3
  • Sung‐Hwan Moon1
  • Taeho Kwon2,3
  1. 1Department of Animal Science and Technology Chung‐Ang University Anseong Republic of Korea
  2. 2Quantum AI Bio Research Laboratory (KJQI‐JQL), Futuristic Animal Resource and Research Center Korea Research Institute of Bioscience and Biotechnology (KRIBB) Cheongju Republic of Korea
  3. 3Advanced Bioconvergence Department KRIBB School, University of Science and Technology (UST) Daejeon Republic of Korea
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Abstract

Stem cell‐based embryo models now reconstruct increasingly advanced stages of mammalian development, but developmental fidelity remains a central limitation. This review examines why cynomolgus monkey systems are biologically necessary, how natural embryos and emerging technologies benchmark primate development, and how advanced monkey embryoids can strengthen interpretation of human embryo models.

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Cite

BibTeXRIS
BibTeX
@article{jeong2026cynomolgus,
  title = {{Cynomolgus Monkey (Macaca fascicularis) Embryo Models: From Developmental Benchmarks to Functionally Testable Embryoids}},
  author = {Yeojeong Jeong and Jongwon Byun and Sung‐Hwan Moon and Taeho Kwon},
  journal = {Journal of Medical Primatology},
  year = {2026},
  month = oct,
  doi = {10.1111/jmp.70123},
  url = {https://doi.org/10.1111/jmp.70123},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Cynomolgus Monkey (Macaca fascicularis) Embryo Models: From Developmental Benchmarks to Functionally Testable Embryoids
AU  - Yeojeong Jeong
AU  - Jongwon Byun
AU  - Sung‐Hwan Moon
AU  - Taeho Kwon
PY  - 2026
DA  - 2026/10/25
JO  - Journal of Medical Primatology
DO  - 10.1111/jmp.70123
UR  - https://doi.org/10.1111/jmp.70123
AB  - Stem cell‐based embryo models now reconstruct increasingly advanced stages of mammalian development, but developmental fidelity remains a central limitation. This review examines why cynomolgus monkey systems are biologically necessary, how natural embryos and emerging technologies benchmark primate development, and how advanced monkey embryoids can strengthen interpretation of human embryo models.
SN  - 0047-2565
SN  - 1600-0684
ER  -