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Peer-reviewedCC BY-NDEFSA journal. European Food Safety Authority

Appethyl® as part of a meal prolongs satiety/reduces cravings after that meal: Evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006.

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Abstract

Following an application from Lars Jansson, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Sweden, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related to 'Appethyl® as part of a meal prolongs satiety/reduces cravings after that meal'. Appethyl® is an aqueous extract from spinach leaves standardised by the manufacturing process and its lipase/colipase inhibition capacity in vitro. The Panel had evaluated the characterisation of Appethyl® in a previous opinion and as there were no changes made to the characterisation of Appethyl® in the current application, the Panel considers the food/constituent sufficiently characterised. The Panel notes that the claimed effect refers to changes in appetite ratings, which are not considered a beneficial physiological effect per se, and that no beneficial physiological effect resulting from changes in appetite ratings has been identified by the applicant. The Panel concludes that a cause-and-effect relationship between the consumption of Appethyl® and a beneficial physiological effect cannot be established in the context of this application.

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BibTeX
@article{efsapanelonnutrition2026appethyl,
  title = {{Appethyl® as part of a meal prolongs satiety/reduces cravings after that meal: Evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006.}},
  author = {EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) and Dominique Turck and Torsten Bohn and Montaña Cámara and Jacqueline Castenmiller and Stefaan de Henauw and Karen-Ildico Hirsch-Ernst and Angeles Jos and Alexandre Maciuk and Inge Mangelsdorf and Breige McNulty and Androniki Naska and Kristina Pentieva and Frank Thies and Ines Drenjančević and Thibault Fiolet and Alfonso Siani},
  journal = {EFSA journal. European Food Safety Authority},
  year = {2026},
  month = oct,
  doi = {10.2903/j.efsa.2026.10384},
  url = {https://europepmc.org/article/MED/42903356},
  note = {CC BY-ND},
}
RIS
TY  - JOUR
TI  - Appethyl® as part of a meal prolongs satiety/reduces cravings after that meal: Evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006.
AU  - EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA)
AU  - Dominique Turck
AU  - Torsten Bohn
AU  - Montaña Cámara
AU  - Jacqueline Castenmiller
AU  - Stefaan de Henauw
AU  - Karen-Ildico Hirsch-Ernst
AU  - Angeles Jos
AU  - Alexandre Maciuk
AU  - Inge Mangelsdorf
AU  - Breige McNulty
AU  - Androniki Naska
AU  - Kristina Pentieva
AU  - Frank Thies
AU  - Ines Drenjančević
AU  - Thibault Fiolet
AU  - Alfonso Siani
PY  - 2026
DA  - 2026/10/20
JO  - EFSA journal. European Food Safety Authority
DO  - 10.2903/j.efsa.2026.10384
UR  - https://europepmc.org/article/MED/42903356
AB  - Following an application from Lars Jansson, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Sweden, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related to 'Appethyl® as part of a meal prolongs satiety/reduces cravings after that meal'. Appethyl® is an aqueous extract from spinach leaves standardised by the manufacturing process and its lipase/colipase inhibition capacity in vitro. The Panel had evaluated the characterisation of Appethyl® in a previous opinion and as there were no changes made to the characterisation of Appethyl® in the current application, the Panel considers the food/constituent sufficiently characterised. The Panel notes that the claimed effect refers to changes in appetite ratings, which are not considered a beneficial physiological effect per se, and that no beneficial physiological effect resulting from changes in appetite ratings has been identified by the applicant. The Panel concludes that a cause-and-effect relationship between the consumption of Appethyl® and a beneficial physiological effect cannot be established in the context of this application.
SN  - 1831-4732
ER  -