Peer-reviewedLicence not statedNeuroscience Bulletin
A Humanized Knock-in Mouse Model of the PSEN1 V97L Mutation from a Major Chinese Alzheimer’s Disease Pedigree Reveals Early Neuroinflammation
- 1Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069 China
- 2Laboratory Animal Resource Center, Capital Medical University, Beijing, 100069 China
- 3Center of Alzheimer’s Disease, Beijing Institute of Brain Disorders, Capital Medical University, Beijing, 100069 China
Related
- Conserved synaptic modifications by humanized tau through diverse isoform- and mutation-specific intracellular interactions
- Deciphering the effects of aging on Alzheimer's disease based on mitochondrial dysfunction and neuroinflammation.
- CD8+ T cells drive neuroinflammation and cognitive decline in Alzheimer’s disease
- Traditional Chinese medicine-related interventions and the cGAS–STING axis in neuroinflammation: disease contexts and mechanisms of action
- Astrocytic endoplasmic reticulum stress as an amplifier of neuroinflammation and neurodegeneration in Alzheimer’s disease: a narrative review
BibTeX
@article{dai2026humanized,
title = {{A Humanized Knock-in Mouse Model of the PSEN1 V97L Mutation from a Major Chinese Alzheimer’s Disease Pedigree Reveals Early Neuroinflammation}},
author = {Lu Dai and Sirong Lv and Huimin Guo and Zizhao Li and Jiaying Li and Yujia Wang and Miaomiao Du and Donghui Wu and Kunhe Ma and Na Wu and Jing Zhang and Baian Chen},
journal = {Neuroscience Bulletin},
year = {2026},
month = jun,
doi = {10.1007/s12264-026-01656-9},
url = {https://doi.org/10.1007/s12264-026-01656-9},
}
RIS
TY - JOUR
TI - A Humanized Knock-in Mouse Model of the PSEN1 V97L Mutation from a Major Chinese Alzheimer’s Disease Pedigree Reveals Early Neuroinflammation
AU - Lu Dai
AU - Sirong Lv
AU - Huimin Guo
AU - Zizhao Li
AU - Jiaying Li
AU - Yujia Wang
AU - Miaomiao Du
AU - Donghui Wu
AU - Kunhe Ma
AU - Na Wu
AU - Jing Zhang
AU - Baian Chen
PY - 2026
DA - 2026/06/23
JO - Neuroscience Bulletin
DO - 10.1007/s12264-026-01656-9
UR - https://doi.org/10.1007/s12264-026-01656-9
SN - 1673-7067
SN - 1995-8218
ER -