Intraoperative Indocyanine Green Fluorescence for Assessment of Suspected Venous Invasion in a Dog With Thyroid Carcinoma.
- 1Department of Veterinary Surgery, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungcheongbuk-do, Republic of Korea.
Abstract
Accurate intraoperative assessment of vascular involvement in canine thyroid carcinoma remains challenging when preoperative imaging findings are equivocal. This case describes the use of intraoperative indocyanine green fluorescence imaging to assist real-time assessment of suspected venous involvement during canine thyroidectomy. A 5-year-old spayed female Maltese dog was presented with a cervical mass and clinicopathological findings consistent with hypothyroidism. Contrast-enhanced computed tomography identified a left thyroid mass with suspected external jugular vein compression but no definitive evidence of vascular invasion. During left thyroidectomy, dilation and distal tapering of the thyroid veins raised concern for venous involvement. Indocyanine green (0.5 mg/dog) was administered intravenously for intraoperative near-infrared fluorescence imaging. Diffuse fluorescence of the thyroid mass and segmental intraluminal fluorescence within the dilated thyroid vein were observed, with signal loss at the tapering point. Based on these findings, en bloc resection including a short segment of the involved vein was performed. Histopathology confirmed thyroid carcinoma without evidence of regional lymph node metastasis. This case illustrates that intraoperative indocyanine green fluorescence imaging may provide adjunctive real-time information for assessing suspected venous involvement during canine thyroid carcinoma surgery and may complement preoperative imaging when vascular invasion is uncertain.
Related
- The Role of Intraoperative Indocyanine Green Fluorescence Angiography in Reducing Anastomotic Leak After Colorectal Resection: A Systematic Review of Randomised Controlled Trials
- Intraoperative indocyanine green fluorescence in canine meningioma: macroscopic visualization, immediate MRI correlation, and clinical outcomes : a case series.
- Prognostic significance of indocyanine green fluorescence patterns in resected hepatocellular carcinoma: a retrospective analysis of prospectively collected data.
- Indocyanine green fluorescence–guided laparoscopic anatomical hepatectomy for radical resection of hepatocellular carcinoma: a clinical study
- Use of Indocyanine Green Fluorescence in the Assessment of Bowel Perfusion in Emergency and Elective Colorectal Surgery: A Retrospective Cohort Study
BibTeX
@article{kim2026intraoperative,
title = {{Intraoperative Indocyanine Green Fluorescence for Assessment of Suspected Venous Invasion in a Dog With Thyroid Carcinoma.}},
author = {Mingyeong Kim and Yujin Kim and Sungin Lee},
journal = {Veterinary medicine and science},
year = {2026},
month = oct,
doi = {10.1002/vms3.71273},
url = {https://europepmc.org/article/MED/42963907},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Intraoperative Indocyanine Green Fluorescence for Assessment of Suspected Venous Invasion in a Dog With Thyroid Carcinoma.
AU - Mingyeong Kim
AU - Yujin Kim
AU - Sungin Lee
PY - 2026
DA - 2026/10/30
JO - Veterinary medicine and science
DO - 10.1002/vms3.71273
UR - https://europepmc.org/article/MED/42963907
AB - Accurate intraoperative assessment of vascular involvement in canine thyroid carcinoma remains challenging when preoperative imaging findings are equivocal. This case describes the use of intraoperative indocyanine green fluorescence imaging to assist real-time assessment of suspected venous involvement during canine thyroidectomy. A 5-year-old spayed female Maltese dog was presented with a cervical mass and clinicopathological findings consistent with hypothyroidism. Contrast-enhanced computed tomography identified a left thyroid mass with suspected external jugular vein compression but no definitive evidence of vascular invasion. During left thyroidectomy, dilation and distal tapering of the thyroid veins raised concern for venous involvement. Indocyanine green (0.5 mg/dog) was administered intravenously for intraoperative near-infrared fluorescence imaging. Diffuse fluorescence of the thyroid mass and segmental intraluminal fluorescence within the dilated thyroid vein were observed, with signal loss at the tapering point. Based on these findings, en bloc resection including a short segment of the involved vein was performed. Histopathology confirmed thyroid carcinoma without evidence of regional lymph node metastasis. This case illustrates that intraoperative indocyanine green fluorescence imaging may provide adjunctive real-time information for assessing suspected venous involvement during canine thyroid carcinoma surgery and may complement preoperative imaging when vascular invasion is uncertain.
SN - 2053-1095
ER -