Skip to content
DraconiticResearch
Search Sources API
197,768 studies31 sourcesUpdated 1 min ago
Peer-reviewedCC BYJA Clinical Reports

Severe hypoxemia caused by right-to-left shunt through a patent foramen ovale associated with right coronary artery malperfusion secondary to acute aortic dissection: a case report

  1. 1Department of Anesthesiology, University of Toyama, 2630
  2. 2Department of Anesthesiology, Toyama Red Cross Hospital

Abstract

Background Right coronary artery malperfusion associated with acute type A aortic dissection can cause right ventricular failure. However, hypoxemia due to a right-to-left shunt through a patent foramen ovale secondary to elevated right-sided cardiac pressure has rarely been described in this setting. Case presentation An 80-year-old woman with acute type A aortic dissection presented with hypoxemia unexplained by pulmonary disease. Transesophageal echocardiography suggested that right ventricular dysfunction associated with right coronary artery malperfusion had contributed to right-to-left shunting through a patent foramen ovale. Following ascending aortic replacement, she developed hypoxemia after separation from cardiopulmonary bypass. Transesophageal echocardiography showed persistent right ventricular dysfunction and worsening of the shunt. Intraoperative optimization of cardiovascular medications improved hemodynamics, reduced the shunt, and improved oxygenation. Conclusions This case suggests that intracardiac right-to-left shunting should be considered in patients with acute aortic dissection and unexplained hypoxemia, and that transesophageal echocardiography may guide perioperative management.

Related

  1. Acute type A dissection with malperfusion: Immediate central repair and complication-specific strategies
    JTCVS techniquesPeer-reviewedCC BYFull textGeneral medicineEurope PMC
  2. Suspected Mesenteric Malperfusion in Acute Type A Aortic Dissection During Pregnancy: A Case Report and Review of Reperfusion‐First Strategies
    Tam Le, Steven Chok, Khuram Khan
    Clinical case reportsPeer-reviewedCC BY-NC-NDFull textGeneral medicineEurope PMC
  3. Organ Malperfusion and Mortality in Acute Type 1 Aortic Dissection with Iliac Extension: A Retrospective Single-Center Study Focused on Mesenteric Malperfusion and the Source–Clearance Hypothesis
    Ali Onder Kilic
    Journal of Clinical MedicinePeer-reviewedCC BY 4.0General medicineCrossref
  4. Risk factors for postoperative hypoxemia in patients with Stanford type A aortic dissection
    Jian Yang, Yanyan Song
    European Journal of Medical ResearchPeer-reviewedCC BYFull textGeneral medicineDOAJ
  5. Coronary artery calcification is not associated with survival in advanced gastric and gastroesophageal junction cancer: a secondary analysis of the EXPAND trial
    Hans-Jonas Meyer, Tihomir Dermendzhiev, Paul-Philipp Jacobs +5
    Journal of Cancer Research and Clinical OncologyPeer-reviewedCC BY 4.0Full textOncologyPMC
BibTeX
@article{takao2026severe,
  title = {{Severe hypoxemia caused by right-to-left shunt through a patent foramen ovale associated with right coronary artery malperfusion secondary to acute aortic dissection: a case report}},
  author = {Naoki Takao and Satori Mori and Keiko Takehana and Tomonori Takazawa},
  journal = {JA Clinical Reports},
  year = {2026},
  month = nov,
  doi = {10.1186/s40981-026-00879-z},
  url = {https://doi.org/10.1186/s40981-026-00879-z},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Severe hypoxemia caused by right-to-left shunt through a patent foramen ovale associated with right coronary artery malperfusion secondary to acute aortic dissection: a case report
AU  - Naoki Takao
AU  - Satori Mori
AU  - Keiko Takehana
AU  - Tomonori Takazawa
PY  - 2026
DA  - 2026/11/08
JO  - JA Clinical Reports
DO  - 10.1186/s40981-026-00879-z
UR  - https://doi.org/10.1186/s40981-026-00879-z
AB  - Background Right coronary artery malperfusion associated with acute type A aortic dissection can cause right ventricular failure. However, hypoxemia due to a right-to-left shunt through a patent foramen ovale secondary to elevated right-sided cardiac pressure has rarely been described in this setting. Case presentation An 80-year-old woman with acute type A aortic dissection presented with hypoxemia unexplained by pulmonary disease. Transesophageal echocardiography suggested that right ventricular dysfunction associated with right coronary artery malperfusion had contributed to right-to-left shunting through a patent foramen ovale. Following ascending aortic replacement, she developed hypoxemia after separation from cardiopulmonary bypass. Transesophageal echocardiography showed persistent right ventricular dysfunction and worsening of the shunt. Intraoperative optimization of cardiovascular medications improved hemodynamics, reduced the shunt, and improved oxygenation. Conclusions This case suggests that intracardiac right-to-left shunting should be considered in patients with acute aortic dissection and unexplained hypoxemia, and that transesophageal echocardiography may guide perioperative management.
SN  - 2363-9024
ER  -