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Peer-reviewedCC BY-NC-NDCirculation Journal

Interpreting Low Pressure Pullback Gradient in Non-Culprit Lesions With Quantitative Flow Ratio ≥0.80

Abstract

0.84, remain prognostically relevant.2 Second, lower PPG suggests a less focal distribution of epicardial resistance, whereas plaque vulnerability, including lipid-rich plaque and thin-cap fibroatheroma, has been associated with higher PPG. 3 Thus, comparison of baseline angiographic severity, QFR distribution, and outcomes between low QFR/high QFR-PPG and low QFR/low QFR-PPG lesions would be informative in determining whether the prognostic signal primarily reflects reduced QFR itself or whether low QFR-PPG carries additional meaning beyond QFR.

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BibTeX
@article{hoshino2026interpreting,
  title = {{Interpreting Low Pressure Pullback Gradient in Non-Culprit Lesions With Quantitative Flow Ratio ≥0.80}},
  author = {Masahiro Hoshino},
  journal = {Circulation Journal},
  year = {2026},
  month = aug,
  doi = {10.1253/circj.cj-26-0406},
  url = {https://www.jstage.jst.go.jp/article/circj/90/9/90_CJ-26-0406/_article},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Interpreting Low Pressure Pullback Gradient in Non-Culprit Lesions With Quantitative Flow Ratio ≥0.80
AU  - Masahiro Hoshino
PY  - 2026
DA  - 2026/08/25
JO  - Circulation Journal
DO  - 10.1253/circj.cj-26-0406
UR  - https://www.jstage.jst.go.jp/article/circj/90/9/90_CJ-26-0406/_article
AB  - 0.84, remain prognostically relevant.2 Second, lower PPG suggests a less focal distribution of epicardial resistance, whereas plaque vulnerability, including lipid-rich plaque and thin-cap fibroatheroma, has been associated with higher PPG. 3 Thus, comparison of baseline angiographic severity, QFR distribution, and outcomes between low QFR/high QFR-PPG and low QFR/low QFR-PPG lesions would be informative in determining whether the prognostic signal primarily reflects reduced QFR itself or whether low QFR-PPG carries additional meaning beyond QFR.
SN  - 1347-4820
SN  - 1346-9843
ER  -