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Peer-reviewedLicence not statedNew England Journal of Medicine

Eplontersen for Transthyretin Amyloid Cardiomyopathy

  • Marianna Fontana1
  • Ahmad Masri2
  • Scott David Solomon3
  • Francesco Cappelli4
  • Margot K. Davis5
  • Pablo García‐Pavía6,7,8
  • Julian David Gillmore1
  • Mazen A Hanna9
  • Laura Piera Obici10
  • Brett Wesley Sperry11
  • Nobuhiro Tahara12
  • Márcia Waddington‐Cruz13,14
13 more authors
  • Olga M. Azevedo15,16
  • Thibaud Damy17
  • Edileide de Barros Correia18
  • MICHEL G. KHOURI19
  • Andriana Nikolova20
  • Stefan Störk21,22
  • Tom Conrad23
  • Qingqing Yang24
  • Brian Lee Claggett3
  • Jersey Chen25
  • Gary T. Brice24
  • Sotirios Tsimikas24
  • Mathew S. Maurer26
26 affiliations
  1. 1National Amyloidosis Centre, Division of Medicine, University College London, Royal Free Hospital, London
  2. 2Division of Cardiovascular Medicine, Oregon Health and Sciences University, Portland
  3. 3Cardiovascular Division, Brigham and Women’s Hospital, Boston
  4. 4Tuscan Regional Amyloidosis Center, Department of Clinical and Experimental Medicine, Careggi University Hospital, Florence, Italy
  5. 5Division of Cardiology, University of British Columbia, Vancouver, Canada
  6. 6Centro Nacional de Investigaciones Cardiovasculares, Madrid
  7. 7Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares, Madrid
  8. 8Department of Cardiology, Hospital Universitario Puerta de Hierro Majadahonda, Instituto de Investigación Sanitaria Puerta de Hierro, Madrid
  9. 9Amyloidosis Center, Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland
  10. 10Amyloidosis Research and Treatment Center, IRCCS Fondazione Policlinico San Matteo, Pavia, Italy
  11. 11Saint Luke’s Mid America Heart Institute, Kansas City, MO
  12. 12Division of Cardiovascular Medicine, Department of Medicine, Kurume University School of Medicine, Kurume, Japan
  13. 13Amyloidosis Center, Complexo Hospitalar Américas–Samaritano-Vitória, Rio de Janeiro
  14. 14Centro de Paramiloidose Antônio Rodrigues de Mello, Amyloidosis Center, University Hospital, Federal University of Rio de Janeiro, Rio de Janeiro
  15. 15Cardiology Department, Unidade Local de Saúde do Alto Ave, Hospital Senhora da Oliveira, Guimarães, Portugal
  16. 16School of Medicine, Minho University, Braga, Portugal
  17. 17Referral Center for Cardiac Amyloidosis, Department of Cardiology, Centre Hospitalier Universitaire Henri Mondor, French Clinical Research Infrastructure Network: Group for Research on Amyloidosis and Care Excellence, Clinical Epidemiology and Aging, INSERM Unité 955, Université Paris-Est Créteil, Créteil, France
  18. 18Dante Pazzanese Institute of Cardiology, São Paulo
  19. 19Division of Cardiology, Department of Medicine, Duke University Health System, Durham, NC
  20. 20Department of Cardiology, Smidt Heart Institute, Cedars–Sinai Medical Center, Los Angeles
  21. 21Department of Epidemiology and Clinical Research, Comprehensive Heart Failure Center, University of Würzburg, Würzburg, Germany
  22. 22Department of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany
  23. 23Statistics, Cardiovascular, Renal, and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD
  24. 24Ionis, Carlsbad, CA
  25. 25Late-Stage Development, Cardiovascular, Renal, and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD
  26. 26Columbia University Irving Medical Center, New York
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Cite

BibTeXRIS
BibTeX
@article{fontana2026eplontersen,
  title = {{Eplontersen for Transthyretin Amyloid Cardiomyopathy}},
  author = {Marianna Fontana and Ahmad Masri and Scott David Solomon and Francesco Cappelli and Margot K. Davis and Pablo García‐Pavía and Julian David Gillmore and Mazen A Hanna and Laura Piera Obici and Brett Wesley Sperry and Nobuhiro Tahara and Márcia Waddington‐Cruz and Olga M. Azevedo and Thibaud Damy and Edileide de Barros Correia and MICHEL G. KHOURI and Andriana Nikolova and Stefan Störk and Tom Conrad and Qingqing Yang and Brian Lee Claggett and Jersey Chen and Gary T. Brice and Sotirios Tsimikas and Mathew S. Maurer},
  journal = {New England Journal of Medicine},
  year = {2026},
  month = aug,
  doi = {10.1056/nejmoa2608510},
  url = {https://hdl.handle.net/2158/1486594},
}
RIS
TY  - JOUR
TI  - Eplontersen for Transthyretin Amyloid Cardiomyopathy
AU  - Marianna Fontana
AU  - Ahmad Masri
AU  - Scott David Solomon
AU  - Francesco Cappelli
AU  - Margot K. Davis
AU  - Pablo García‐Pavía
AU  - Julian David Gillmore
AU  - Mazen A Hanna
AU  - Laura Piera Obici
AU  - Brett Wesley Sperry
AU  - Nobuhiro Tahara
AU  - Márcia Waddington‐Cruz
AU  - Olga M. Azevedo
AU  - Thibaud Damy
AU  - Edileide de Barros Correia
AU  - MICHEL G. KHOURI
AU  - Andriana Nikolova
AU  - Stefan Störk
AU  - Tom Conrad
AU  - Qingqing Yang
AU  - Brian Lee Claggett
AU  - Jersey Chen
AU  - Gary T. Brice
AU  - Sotirios Tsimikas
AU  - Mathew S. Maurer
PY  - 2026
DA  - 2026/08/28
JO  - New England Journal of Medicine
DO  - 10.1056/nejmoa2608510
UR  - https://hdl.handle.net/2158/1486594
SN  - 0028-4793
SN  - 0096-6762
SN  - 1533-4406
SN  - 2331-4710
ER  -