Food-Derived Substances and Edible Chinese Medicinal Materials in Psoriasis Management: Potential, Evidence, and Perspectives-A Narrative Review.
- 1The First Clinical Medical College, Gansu University of Chinese Medicine, Lanzhou, Gansu, People's Republic of China.
- 2Department of Dermatology, Gansu Provincial People's Hospital, Lanzhou, Gansu, People's Republic of China.
Abstract
Background
Psoriasis is a chronic inflammatory skin disease mediated by immune dysregulation, with a prolonged course, high recurrence rate, and limited curative options. Biologics are effective but costly, carry immunosuppressive risks, and are associated with relapse after discontinuation.Objective
To review the potential mechanisms by which food-derived substances and edible Chinese medicinal materials improve psoriasis through immunomodulation, oxidative stress mitigation, and gut microbiota regulation, and to grade the clinical evidence descriptively.Methods
This is a narrative review, not a systematic review. Literature was searched in PubMed, Web of Science, Cochrane Library, CNKI, and Wanfang up to June 2026. Search terms included psoriasis, diet, nutrition, microbiota, metabolism, and Traditional Chinese Medicine. Evidence grading was informed by the GRADE framework, but no formal GRADE assessment was performed.Main findings
The Mediterranean diet and weight-loss interventions have relatively higher levels of evidence. Omega-3 polyunsaturated fatty acids, bioavailable curcumin, specific probiotic strains, and some medicine-food homologous Chinese herbs show potential adjunctive benefits, but most studies are small, single-center, and lack blinding. Traditional applications of honeysuckle, wolfberry, and Coix seed are gradually being explained by modern pharmacology.Conclusion
Dietary and medicine-food homologous interventions may serve as adjuncts in psoriasis management but cannot replace conventional treatment. High-quality multicenter RCTs are needed to confirm efficacy and safety.
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BibTeX
@article{ma2026foodderived,
title = {{Food-Derived Substances and Edible Chinese Medicinal Materials in Psoriasis Management: Potential, Evidence, and Perspectives-A Narrative Review.}},
author = {Xiaoqin Ma and Shuniu Zheng and Jinjin Kai and Xianwei Wu},
journal = {Clinical, cosmetic and investigational dermatology},
year = {2026},
month = oct,
doi = {10.2147/ccid.s643906},
url = {https://europepmc.org/article/MED/42928794},
note = {CC BY-NC},
}
RIS
TY - JOUR
TI - Food-Derived Substances and Edible Chinese Medicinal Materials in Psoriasis Management: Potential, Evidence, and Perspectives-A Narrative Review.
AU - Xiaoqin Ma
AU - Shuniu Zheng
AU - Jinjin Kai
AU - Xianwei Wu
PY - 2026
DA - 2026/10/21
JO - Clinical, cosmetic and investigational dermatology
DO - 10.2147/ccid.s643906
UR - https://europepmc.org/article/MED/42928794
AB - Background Psoriasis is a chronic inflammatory skin disease mediated by immune dysregulation, with a prolonged course, high recurrence rate, and limited curative options. Biologics are effective but costly, carry immunosuppressive risks, and are associated with relapse after discontinuation.Objective To review the potential mechanisms by which food-derived substances and edible Chinese medicinal materials improve psoriasis through immunomodulation, oxidative stress mitigation, and gut microbiota regulation, and to grade the clinical evidence descriptively.Methods This is a narrative review, not a systematic review. Literature was searched in PubMed, Web of Science, Cochrane Library, CNKI, and Wanfang up to June 2026. Search terms included psoriasis, diet, nutrition, microbiota, metabolism, and Traditional Chinese Medicine. Evidence grading was informed by the GRADE framework, but no formal GRADE assessment was performed.Main findings The Mediterranean diet and weight-loss interventions have relatively higher levels of evidence. Omega-3 polyunsaturated fatty acids, bioavailable curcumin, specific probiotic strains, and some medicine-food homologous Chinese herbs show potential adjunctive benefits, but most studies are small, single-center, and lack blinding. Traditional applications of honeysuckle, wolfberry, and Coix seed are gradually being explained by modern pharmacology.Conclusion Dietary and medicine-food homologous interventions may serve as adjuncts in psoriasis management but cannot replace conventional treatment. High-quality multicenter RCTs are needed to confirm efficacy and safety.
SN - 1178-7015
ER -