Disparities in treatment burden in Peru among people with multiple long-term conditions by geography and healthcare facility: A cross-sectional study
14 affiliations
- 1CRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru
- 2Department of Medicine, Faculty of Medicine, Universidad Peruana Cayetano Heredia, Lima, Peru
- 3Center for research in Primary Health Care, Universidad Peruana Cayetano Heredia, Lima, Peru
- 4Research Department of Primary Care and Population Health, University College London, London, United Kingdom
- 5Department of General Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America
- 6Departments of Neurology, Global Health, Medicine (Infectious Diseases), and Epidemiology, University of Washington, Seattle, Washington, United States of America
- 7Knowledge and Evaluation Research Unit, Mayo Clinic, Rochester, Minnesota, United States of America
- 8Faculty of Medicine, Universidad de San Martín de Porres, Lima, Peru
- 9Department of Internal Medicina, Clínica Internacional, Lima, Peru
- 10School of Medicine, Universidad Peruana Union, Lima, Peru
- 11Department of Medicine, Clínica Good Hope, Lima, Peru
- 12Corporate Medical Directorate, Clínica Médica Cayetano Heredia, Lima, Perú
- 13Department of Postgraduate Studies, School of Medicine, Universidad Peruana Cayetano Heredia, Lima, Peru
- 14Department of Endocrinology, Hospital Arzobispo Loayza, Lima, Perú
Abstract
People with multiple long-term conditions (MLTC) in low-resource settings face high treatment burdens, influenced by healthcare access and quality disparities. The study aimed to compare the treatment burden among patients with MLTC across geographical locations and healthcare providers in Peru. We conducted a cross-sectional study conducted between June–October 2023 among outpatients aged ≥40 years with type 2 diabetes and ≥1 additional chronic condition, recruited from public and private healthcare facilities in urban Lima and semi-urban Tumbes, Peru. Treatment burden was assessed using the Multimorbidity Treatment Burden Questionnaire (MTBQ). Differences in median MTBQ scores by setting and healthcare provider were analyzed using regression models adjusting for capacity- and workload-related variables. Among 555 participants (55% female, mean age 62.4 ± 10.5 years), median MTBQ score was 27.1 (IQR 14.6-41.7). After adjustment, patients in semi-urban Tumbes had higher treatment burden than those in urban Lima (adjusted median difference 6.1 points; 95% CI 2.9 to 9.3), while patients receiving care in private facilities had lower treatment burden than those in public settings (−6.6 points; 95% CI −9.3 to −3.9). These findings highlight substantial inequalities in treatment burden by place and provider type, with implications for efforts to improve care delivery and reduce disparities for people living with MLTC.
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BibTeX
@article{perezleon2026disparities,
title = {{Disparities in treatment burden in Peru among people with multiple long-term conditions by geography and healthcare facility: A cross-sectional study}},
author = {Silvana Perez-Leon and Daniel Mendoza-Quispe and Maria Sofia Cuba-Fuentes and Juan Carlos Bazo-Alvarez and M. Amalia Pesantes and Andrea Gaspar and Joseph R. Zunt and Victor M. Montori and Jose Armando Castillo and Eduardo Carcausto and Nelson Diaz and Keveen Salirrosas and Pilar Cornejo and J. Jaime Miranda},
journal = {PLOS Global Public Health},
year = {2026},
month = sep,
doi = {10.1371/journal.pgph.0007355},
url = {https://journals.plos.org/globalpublichealth/article?id=10.1371/journal.pgph.0007355},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Disparities in treatment burden in Peru among people with multiple long-term conditions by geography and healthcare facility: A cross-sectional study
AU - Silvana Perez-Leon
AU - Daniel Mendoza-Quispe
AU - Maria Sofia Cuba-Fuentes
AU - Juan Carlos Bazo-Alvarez
AU - M. Amalia Pesantes
AU - Andrea Gaspar
AU - Joseph R. Zunt
AU - Victor M. Montori
AU - Jose Armando Castillo
AU - Eduardo Carcausto
AU - Nelson Diaz
AU - Keveen Salirrosas
AU - Pilar Cornejo
AU - J. Jaime Miranda
PY - 2026
DA - 2026/09/29
JO - PLOS Global Public Health
DO - 10.1371/journal.pgph.0007355
UR - https://journals.plos.org/globalpublichealth/article?id=10.1371/journal.pgph.0007355
AB - People with multiple long-term conditions (MLTC) in low-resource settings face high treatment burdens, influenced by healthcare access and quality disparities. The study aimed to compare the treatment burden among patients with MLTC across geographical locations and healthcare providers in Peru. We conducted a cross-sectional study conducted between June–October 2023 among outpatients aged ≥40 years with type 2 diabetes and ≥1 additional chronic condition, recruited from public and private healthcare facilities in urban Lima and semi-urban Tumbes, Peru. Treatment burden was assessed using the Multimorbidity Treatment Burden Questionnaire (MTBQ). Differences in median MTBQ scores by setting and healthcare provider were analyzed using regression models adjusting for capacity- and workload-related variables. Among 555 participants (55% female, mean age 62.4 ± 10.5 years), median MTBQ score was 27.1 (IQR 14.6-41.7). After adjustment, patients in semi-urban Tumbes had higher treatment burden than those in urban Lima (adjusted median difference 6.1 points; 95% CI 2.9 to 9.3), while patients receiving care in private facilities had lower treatment burden than those in public settings (−6.6 points; 95% CI −9.3 to −3.9). These findings highlight substantial inequalities in treatment burden by place and provider type, with implications for efforts to improve care delivery and reduce disparities for people living with MLTC.
SN - 2767-3375
ER -