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Peer-reviewedCC BY 4.0Pain Research & Management

The Characteristics and Clinical Evolution of Adolescents With Severe Chronic Pain in an Inpatient Multimodal Pain Programme

  • Guillaume Groffe1,2
  • Aminata Ali3,4
  • France Hirot3,4
  • Adrien Naddaf3
  • Anne Tonelli1,5
  • Didier Bouhassira6
  • Nathalie Godart1,2,3,4,7
  • Chantal Stheneur1,2,3,5,7
7 affiliations
  1. 1Fondation Santé des Etudiants de France University Center for Adolescent and Young Adult Health Paris 75016 France
  2. 2UFR Simone Veil-Santé Université Versailles Saint-Quentin-en-Yvelines 78180 Montigny-le-Bretonneux France
  3. 3Fondation Santé des Etudiants de France University Center for Adolescent and Young Adult Health Paris 75014 France
  4. 4Equipe DevPsy Centre de Recherche en Épidémiologie et Santé des Populations (CESP) Hôpital Paul Brousse Université Paris-Saclay 94807 Villejuif France universite-paris-saclay.fr
  5. 5Groupe de Recherche en Médecine et Santé de l’Adolescent (GRMSA) Paris France
  6. 6Inserm U987 UVSQ Ambroise-Paré Hospital Paris-Saclay University Boulogne-Billancourt France universite-paris-saclay.fr
  7. 7Inserm U1178 UVSQ André Mignot Hospital Paris-Saclay University Versailles France universite-paris-saclay.fr
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Abstract

Objectives: Around 5.1% of the French pediatric general population experiences severe chronic pain; it leads to school absenteeism, social isolation, depressed mood and anxiety. Only a few studies have been conducted on inpatient treatment for severe chronic pain. The aim of this research was to describe the characteristics of adolescents enrolled in an inpatient pain management programme within a residential therapeutic care center and their outcomes at discharge.

Methods: We conducted a retrospective chart review of patients aged 11–19 who were hospitalized between 2010 and 2020.

Results: We identified 196 hospitalizations for 195 adolescents. Their mean age was 15.4 ± 2.1 years, and 67.7% were female. Before admission, 92.9% experienced school absenteeism. At discharge, the mean number of weak‐ and strong‐opioid painkillers and/or chronic pain drugs prescribed was significantly reduced (mean difference = −0.70 ± 0.90, p < 0.001) and pain intensity was significantly lower than at admission on a 10‐point numerical scale (mean = 4.6 ± 2.5 at admission vs. 2.8 ± 3.3 at discharge (p = 0.01)). A school reintegration programme was documented for 167/196 (85.2%) hospitalizations.

Discussion and Conclusion: Adolescents admitted to this inpatient programme presented with severe chronic pain, substantial school absenteeism, and a long history of healthcare utilization. At discharge, lower pain intensity, reduced painkiller prescriptions, reported improvements in social participation, and planned school reintegration were documented. These findings suggest that intensive multidisciplinary inpatient programmes may represent a valuable rehabilitation option for adolescents with complex chronic pain who remain significantly disabled despite specialized outpatient management and warrant further prospective evaluation.

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Cite

BibTeXRIS
BibTeX
@article{groffe2026characteristics,
  title = {{The Characteristics and Clinical Evolution of Adolescents With Severe Chronic Pain in an Inpatient Multimodal Pain Programme}},
  author = {Guillaume Groffe and Aminata Ali and France Hirot and Adrien Naddaf and Anne Tonelli and Didier Bouhassira and Nathalie Godart and Chantal Stheneur},
  journal = {Pain Research \& Management},
  year = {2026},
  month = nov,
  doi = {10.1155/prm/6041949},
  url = {https://doi.org/10.1155/prm/6041949},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - The Characteristics and Clinical Evolution of Adolescents With Severe Chronic Pain in an Inpatient Multimodal Pain Programme
AU  - Guillaume Groffe
AU  - Aminata Ali
AU  - France Hirot
AU  - Adrien Naddaf
AU  - Anne Tonelli
AU  - Didier Bouhassira
AU  - Nathalie Godart
AU  - Chantal Stheneur
PY  - 2026
DA  - 2026/11/02
JO  - Pain Research & Management
DO  - 10.1155/prm/6041949
UR  - https://doi.org/10.1155/prm/6041949
AB  - Objectives: Around 5.1% of the French pediatric general population experiences severe chronic pain; it leads to school absenteeism, social isolation, depressed mood and anxiety. Only a few studies have been conducted on inpatient treatment for severe chronic pain. The aim of this research was to describe the characteristics of adolescents enrolled in an inpatient pain management programme within a residential therapeutic care center and their outcomes at discharge.  Methods: We conducted a retrospective chart review of patients aged 11–19 who were hospitalized between 2010 and 2020.  Results: We identified 196 hospitalizations for 195 adolescents. Their mean age was 15.4 ± 2.1 years, and 67.7% were female. Before admission, 92.9% experienced school absenteeism. At discharge, the mean number of weak‐ and strong‐opioid painkillers and/or chronic pain drugs prescribed was significantly reduced (mean difference = −0.70 ± 0.90, p < 0.001) and pain intensity was significantly lower than at admission on a 10‐point numerical scale (mean = 4.6 ± 2.5 at admission vs. 2.8 ± 3.3 at discharge (p = 0.01)). A school reintegration programme was documented for 167/196 (85.2%) hospitalizations.  Discussion and Conclusion: Adolescents admitted to this inpatient programme presented with severe chronic pain, substantial school absenteeism, and a long history of healthcare utilization. At discharge, lower pain intensity, reduced painkiller prescriptions, reported improvements in social participation, and planned school reintegration were documented. These findings suggest that intensive multidisciplinary inpatient programmes may represent a valuable rehabilitation option for adolescents with complex chronic pain who remain significantly disabled despite specialized outpatient management and warrant further prospective evaluation.
SN  - 1203-6765
SN  - 1918-1523
ER  -