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Peer-reviewedCC BY 4.0Current Medical Mycology

Rare Ocular Foe: A Case of Fungal Keratitis Caused by Podospora bulbillosa

  • Madhu Rai1
  • Vaibhav Nagpal2
  • Chaitali Nikam3
  • Anirvan Chatterjee3
  • Amrutraj Zade3
  • Sourav Das4
  • Savitri Sharma1
4 affiliations
  1. 1Ocular Microbiology Service, Shantilal Shanghvi Eye Institute, Wadala East, Mumbai, Maharashtra, India
  2. 2Junior Faculty, Cornea Service, Shantilal Shanghvi Eye Institute, Wadala East, Mumbai, Maharashtra, India
  3. 3Haystack Analytics Private Limited SINE, IIT Bombay, Powai, Mumbai, India
  4. 4Jhaveri Microbiology Centre, L V Prasad Eye Institute, Hyderabad, Telangana, India
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Abstract

Background and Purpose:: Fungal keratitis is commonly caused by filamentous fungi following trauma or environmental exposure. This study aimed to report a rare case of fungal keratitis confirmed using Oxford Nanopore Sequencing.

Case presentation:: A 25-year-old male developed pain and redness in his right eye after dust exposure. Slit-lamp examination showed a superficial corneal infiltrate with vision 20/50 in the affected eye. Microscopy revealed septate fungal filaments, and SDA culture produced rapidly growing colonies that turned black. Sequencing and phylogenetic analysis identified the fungus as Podospora bulbillosa. The patient responded well to 5% natamycin, achieving complete healing.

Conclusion:: The case reported here emphasized the susceptibility of the cornea to rare fungal pathogens and the importance of timely selection of appropriate antifungal therapy.

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Cite

BibTeXRIS
BibTeX
@article{rai2026rare,
  title = {{Rare Ocular Foe: A Case of Fungal Keratitis Caused by Podospora bulbillosa}},
  author = {Madhu Rai and Vaibhav Nagpal and Chaitali Nikam and Anirvan Chatterjee and Amrutraj Zade and Sourav Das and Savitri Sharma},
  journal = {Current Medical Mycology},
  year = {2026},
  month = jul,
  doi = {10.22034/cmm.2026.345427.1677},
  url = {https://doi.org/10.22034/cmm.2026.345427.1677},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Rare Ocular Foe: A Case of Fungal Keratitis Caused by Podospora bulbillosa
AU  - Madhu Rai
AU  - Vaibhav Nagpal
AU  - Chaitali Nikam
AU  - Anirvan Chatterjee
AU  - Amrutraj Zade
AU  - Sourav Das
AU  - Savitri Sharma
PY  - 2026
DA  - 2026/07/29
JO  - Current Medical Mycology
DO  - 10.22034/cmm.2026.345427.1677
UR  - https://doi.org/10.22034/cmm.2026.345427.1677
AB  - Background and Purpose:: Fungal keratitis is commonly caused by filamentous fungi following trauma or environmental exposure. This study aimed to report a rare case of fungal keratitis confirmed using Oxford Nanopore Sequencing.  Case presentation:: A 25-year-old male developed pain and redness in his right eye after dust exposure. Slit-lamp examination showed a superficial corneal infiltrate with vision 20/50 in the affected eye. Microscopy revealed septate fungal filaments, and SDA culture produced rapidly growing colonies that turned black. Sequencing and phylogenetic analysis identified the fungus as Podospora bulbillosa. The patient responded well to 5% natamycin, achieving complete healing.  Conclusion:: The case reported here emphasized the susceptibility of the cornea to rare fungal pathogens and the importance of timely selection of appropriate antifungal therapy.
SN  - 2423-3439
SN  - 2423-3420
ER  -