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Peer-reviewedCC BY-NC-ND 4.0ACS Omega

Nickel-Catalyzed Thiolative Cyclization of Cyclic Enynones under Visible-Light Irradiation: An Easy Access to 9-Sulfenyl-2,3-dihydrophenanthren-4(1 H )-ones

  • Arundhati Sahu1
  • Kanagaraj Madasamy2
  • Baburaj Baskar3
  • Subramaniyan Mannathan1
  1. 1SRM University-AP , , , ,
  2. 2Sona College of Technology , , , ,
  3. 3SRM Institute of Science and Technology , , , ,
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Abstract

An efficient nickel-catalyzed thiolative addition–cyclization of conjugated cyclic enynones for the synthesis of 9-sulfenyl-2,3-dihydrophenanthren-4(1H)-ones is described. The reaction proceeds through a nickel-catalyzed hydrothiolation of cyclic enynones, followed by visible-light-induced intramolecular cyclization. This protocol tolerates both aromatic and aliphatic thiols, affording sulfur-containing dihydrophenanthrenes in good to high yields. The synthetic utility of the method is further demonstrated by converting the obtained products into valuable phenanthrene derivatives.

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Cite

BibTeXRIS
BibTeX
@article{sahu2026nickelcatalyzed,
  title = {{Nickel-Catalyzed Thiolative Cyclization of Cyclic Enynones under Visible-Light Irradiation: An Easy Access to 9-Sulfenyl-2,3-dihydrophenanthren-4(1 H )-ones}},
  author = {Arundhati Sahu and Kanagaraj Madasamy and Baburaj Baskar and Subramaniyan Mannathan},
  journal = {ACS Omega},
  year = {2026},
  month = oct,
  doi = {10.1021/acsomega.6c07949},
  url = {https://pubs.acs.org/acsodf/article/11/42/65389/5451291/Nickel-Catalyzed-Thiolative-Cyclization-of-Cyclic},
  note = {CC BY-NC-ND 4.0},
}
RIS
TY  - JOUR
TI  - Nickel-Catalyzed Thiolative Cyclization of Cyclic Enynones under Visible-Light Irradiation: An Easy Access to 9-Sulfenyl-2,3-dihydrophenanthren-4(1 H )-ones
AU  - Arundhati Sahu
AU  - Kanagaraj Madasamy
AU  - Baburaj Baskar
AU  - Subramaniyan Mannathan
PY  - 2026
DA  - 2026/10/14
JO  - ACS Omega
DO  - 10.1021/acsomega.6c07949
UR  - https://pubs.acs.org/acsodf/article/11/42/65389/5451291/Nickel-Catalyzed-Thiolative-Cyclization-of-Cyclic
AB  - An efficient nickel-catalyzed thiolative addition–cyclization of conjugated cyclic enynones for the synthesis of 9-sulfenyl-2,3-dihydrophenanthren-4(1H)-ones is described. The reaction proceeds through a nickel-catalyzed hydrothiolation of cyclic enynones, followed by visible-light-induced intramolecular cyclization. This protocol tolerates both aromatic and aliphatic thiols, affording sulfur-containing dihydrophenanthrenes in good to high yields. The synthetic utility of the method is further demonstrated by converting the obtained products into valuable phenanthrene derivatives.
SN  - 2470-1343
ER  -