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PreprintCC0medRxiv

Congenital syphilis outcomes by penicillin dosing intervals among women with late latent or latent of unknown duration syphilis during pregnancy in eight U.S. jurisdictions: 2018-2023

  • E. Martinson1
  • E. L. Lewis
  • S. Newton
  • J. M. Carlson
  • K. Miele
  • K. P. O'Callaghan
  • B. Anderson
  • T. Falzarano
  • T. R. Levin
  • M. Jayroe
  • C. M. Johnson
  • N. D. Longcore
4 more authors
  • A. Berryhill
  • T. Willabus
  • K. R. Woodworth
  • V. T. Tong
  1. 1Division of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atl
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Abstract

Pregnant women with late latent or latent of unknown duration syphilis are recommended to receive three doses of benzathine penicillin G each 9 or fewer days apart; data on interval variations are limited. We found no significant difference in risk of congenital syphilis between 9-day and 6-8 day dosing intervals.

SummaryAmong pregnant women with late latent or latent of unknown duration syphilis, there was no difference in risk of congenital syphilis between 9-day and 6-8 day maternal treatment dosing intervals.

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Cite

BibTeXRIS
BibTeX
@misc{martinson2026congenital,
  title = {{Congenital syphilis outcomes by penicillin dosing intervals among women with late latent or latent of unknown duration syphilis during pregnancy in eight U.S. jurisdictions: 2018-2023}},
  author = {E. Martinson and E. L. Lewis and S. Newton and J. M. Carlson and K. Miele and K. P. O'Callaghan and B. Anderson and T. Falzarano and T. R. Levin and M. Jayroe and C. M. Johnson and N. D. Longcore and A. Berryhill and T. Willabus and K. R. Woodworth and V. T. Tong},
  howpublished = {medRxiv},
  year = {2026},
  month = sep,
  doi = {10.64898/2026.09.03.26361028},
  url = {https://www.medrxiv.org/content/10.64898/2026.09.03.26361028v1},
  note = {CC0},
}
RIS
TY  - UNPB
TI  - Congenital syphilis outcomes by penicillin dosing intervals among women with late latent or latent of unknown duration syphilis during pregnancy in eight U.S. jurisdictions: 2018-2023
AU  - E. Martinson
AU  - E. L. Lewis
AU  - S. Newton
AU  - J. M. Carlson
AU  - K. Miele
AU  - K. P. O'Callaghan
AU  - B. Anderson
AU  - T. Falzarano
AU  - T. R. Levin
AU  - M. Jayroe
AU  - C. M. Johnson
AU  - N. D. Longcore
AU  - A. Berryhill
AU  - T. Willabus
AU  - K. R. Woodworth
AU  - V. T. Tong
PY  - 2026
DA  - 2026/09/03
PB  - medRxiv
DO  - 10.64898/2026.09.03.26361028
UR  - https://www.medrxiv.org/content/10.64898/2026.09.03.26361028v1
AB  - Pregnant women with late latent or latent of unknown duration syphilis are recommended to receive three doses of benzathine penicillin G each 9 or fewer days apart; data on interval variations are limited. We found no significant difference in risk of congenital syphilis between 9-day and 6-8 day dosing intervals.  SummaryAmong pregnant women with late latent or latent of unknown duration syphilis, there was no difference in risk of congenital syphilis between 9-day and 6-8 day maternal treatment dosing intervals.
ER  -