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Peer-reviewedCC BY 4.0Case Reports in Anesthesiology

Perioperative Anesthesia: Botulinum Toxin Injection in a 6‐Year‐Old Female With “No Burp Disease”

  1. 1School of Medicine Indiana University Evansville Indiana USA indiana.edu
  2. 2Anesthesia Service Deaconess Health System Evansville Indiana USA deaconess.com
  3. 3Deaconess Health System Evansville Indiana USA deaconess.com

Abstract

Retrograde cricopharyngeus dysfunction is a chronic condition involving inability of the cricopharyngeal muscle to relax in a task‐specific manner (eructation). Symptoms commonly include bloating, significant discomfort, excessive flatulence, and often self‐imposed limitations in oral diet and activity. Here, we report a 6‐year‐old patient with several years of symptoms who underwent surgical injection of botulinum toxin under general anesthesia. Anesthesia with propofol and sevoflurane provided adequate sedation and analgesia. Nitrous oxide was avoided due to theoretical concern for impaired ability to clear esophageal and abdominal gas which can lead to postoperative nausea, vomiting, and aspiration risk.

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BibTeX
@article{applewhite2026perioperative,
  title = {{Perioperative Anesthesia: Botulinum Toxin Injection in a 6‐Year‐Old Female With “No Burp Disease”}},
  author = {Logan D. Applewhite and Lawrence D. Garcia-Reyes and Paul M. Weinberger},
  journal = {Case Reports in Anesthesiology},
  year = {2026},
  month = nov,
  doi = {10.1155/cria/1726887},
  url = {https://doi.org/10.1155/cria/1726887},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Perioperative Anesthesia: Botulinum Toxin Injection in a 6‐Year‐Old Female With “No Burp Disease”
AU  - Logan D. Applewhite
AU  - Lawrence D. Garcia-Reyes
AU  - Paul M. Weinberger
PY  - 2026
DA  - 2026/11/03
JO  - Case Reports in Anesthesiology
DO  - 10.1155/cria/1726887
UR  - https://doi.org/10.1155/cria/1726887
AB  - Retrograde cricopharyngeus dysfunction is a chronic condition involving inability of the cricopharyngeal muscle to relax in a task‐specific manner (eructation). Symptoms commonly include bloating, significant discomfort, excessive flatulence, and often self‐imposed limitations in oral diet and activity. Here, we report a 6‐year‐old patient with several years of symptoms who underwent surgical injection of botulinum toxin under general anesthesia. Anesthesia with propofol and sevoflurane provided adequate sedation and analgesia. Nitrous oxide was avoided due to theoretical concern for impaired ability to clear esophageal and abdominal gas which can lead to postoperative nausea, vomiting, and aspiration risk.
SN  - 2090-6382
SN  - 2090-6390
ER  -