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Peer-reviewedCC BYInternational Journal of Infectious Diseases

Antibiotic self-medication and public awareness during the 2023 Gaza war: a cross-sectional investigation

  1. 1Department of Medical Laboratory Sciences, Faculty of Health Sciences, Islamic University Gaza, Gaza, Palestine; Corresponding author. Department of Medical Laboratory Sciences, Faculty of Health Sciences, Islamic University Gaza, University Street, Rimal, P.O. Box 108, Gaza, Palestine.
  2. 2Faculty of Health Sciences, The Islamic University, Gaza, Palestine

Abstract

Background: Antimicrobial resistance is driven by inappropriate antibiotic use, particularly self-medication. The 2023 Gaza War disrupted healthcare services, increasing resistant infections and reliance on self-treatment practices. Objectives: To determine the prevalence of antibiotic self-medication and assess public awareness during the 2023 Gaza War. Methods: A cross-sectional survey was conducted between May and October 2025 among adults residing in the Gaza Strip during the 2023 Gaza War. A multistage nonprobability recruitment strategy, organized across predefined governorate and residential-setting strata, was used to recruit 422 participants from primary healthcare centers, community pharmacies, and displacement shelters. The questionnaire demonstrated good internal consistency (Cronbach’s α = 0.857). Ethical approval was obtained from the relevant institutional review board, and informed consent was secured from all participants. Results: The overall KAP score was moderate (67.46%), with attitudes scoring highest (74.62%), followed by knowledge (66.23%) and practices (61.52%). Reported antibiotic self-medication increased from 60.4% before the war to 80.6% during the war ( P < 0.001), with significant changes in reasons for self-medication and antibiotic procurement sources. The mean antimicrobial-resistance perception score was 82.19% ± 11.10%, and knowledge was strongly correlated with the total KAP score (r = 0.836, P < 0.001). Conclusions: Reported antibiotic self-medication was markedly higher during the 2023 Gaza War despite moderate public awareness, highlighting the urgent need for education, antibiotic stewardship, and improved healthcare accessibility.

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BibTeX
@article{altalla2026antibiotic,
  title = {{Antibiotic self-medication and public awareness during the 2023 Gaza war: a cross-sectional investigation}},
  author = {Sundus A. Altalla and Ayman M. Abu Mustafa and Abdelraouf A. Elmanama},
  journal = {International Journal of Infectious Diseases},
  year = {2026},
  month = oct,
  doi = {10.1016/j.ijid.2026.109090},
  url = {https://doi.org/10.1016/j.ijid.2026.109090},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Antibiotic self-medication and public awareness during the 2023 Gaza war: a cross-sectional investigation
AU  - Sundus A. Altalla
AU  - Ayman M. Abu Mustafa
AU  - Abdelraouf A. Elmanama
PY  - 2026
DA  - 2026/10/30
JO  - International Journal of Infectious Diseases
DO  - 10.1016/j.ijid.2026.109090
UR  - https://doi.org/10.1016/j.ijid.2026.109090
AB  - Background: Antimicrobial resistance is driven by inappropriate antibiotic use, particularly self-medication. The 2023 Gaza War disrupted healthcare services, increasing resistant infections and reliance on self-treatment practices. Objectives: To determine the prevalence of antibiotic self-medication and assess public awareness during the 2023 Gaza War. Methods: A cross-sectional survey was conducted between May and October 2025 among adults residing in the Gaza Strip during the 2023 Gaza War. A multistage nonprobability recruitment strategy, organized across predefined governorate and residential-setting strata, was used to recruit 422 participants from primary healthcare centers, community pharmacies, and displacement shelters. The questionnaire demonstrated good internal consistency (Cronbach’s α = 0.857). Ethical approval was obtained from the relevant institutional review board, and informed consent was secured from all participants. Results: The overall KAP score was moderate (67.46%), with attitudes scoring highest (74.62%), followed by knowledge (66.23%) and practices (61.52%). Reported antibiotic self-medication increased from 60.4% before the war to 80.6% during the war ( P < 0.001), with significant changes in reasons for self-medication and antibiotic procurement sources. The mean antimicrobial-resistance perception score was 82.19% ± 11.10%, and knowledge was strongly correlated with the total KAP score (r = 0.836, P < 0.001). Conclusions: Reported antibiotic self-medication was markedly higher during the 2023 Gaza War despite moderate public awareness, highlighting the urgent need for education, antibiotic stewardship, and improved healthcare accessibility.
SN  - 1201-9712
SN  - 1878-3511
ER  -