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Peer-reviewedCC BYJTCVS open

Saphenous vein grafts from thigh versus calf: Comparison of angiographic patency and clinical outcomes.

  • Suk Ho Sohn1
  • Hee Ju Hong1
  • Suji Oh1
  • Yuri Lee1
  • Yoonjin Kang1
  • Jae Woong Choi1
  • Ho Young Hwang1
  1. 1Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
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Abstract

Objectives

This study compared angiographic patency and clinical outcomes between patients who received saphenous vein (SV) grafts from the upper leg (UL) and those who received grafts from the lower leg (LL) for coronary artery bypass grafting (CABG).Methods

A total of 1630 patients who received primary isolated off-pump CABG using the SV harvested via the no-touch technique from the UL (UL group, n = 203) or the LL (LL group, n = 1427) were enrolled in this study. Propensity score matching was performed, and 202 pairs were matched. Early, 1-year, and 5-year graft angiograms were obtained for 99.5%, 85.7%, and 31.2% of the cohort, respectively. The median follow-up duration was 85.8 months. The primary outcome was midterm angiographic patency, and the secondary outcomes were midterm clinical outcomes.Results

There was no significant difference in baseline characteristics between the matched groups. Early clinical outcomes, including operative mortality (0.8%, 13 out of 1630), demonstrated no intergroup differences. Angiographic patency for SV grafts was not significantly different at early (98.3% vs 98.5% in the UL group vs the LL group, P = .80), 1-year (94.8% vs 95.4% in the UL group vs the LL group, P = .74), or 5-year evaluation (97.8% vs 96.0% in the UL group vs the LL group, P = .43). Midterm survival up to 7 years was comparable between the groups (P = .81).Conclusions

SV grafts from the UL demonstrated comparable 5-year angiographic patency and 7-year clinical outcomes compared with those from the LL during off-pump CABG.

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Cite

BibTeXRIS
BibTeX
@article{sohn2026saphenous,
  title = {{Saphenous vein grafts from thigh versus calf: Comparison of angiographic patency and clinical outcomes.}},
  author = {Suk Ho Sohn and Hee Ju Hong and Suji Oh and Yuri Lee and Yoonjin Kang and Jae Woong Choi and Ho Young Hwang},
  journal = {JTCVS open},
  year = {2026},
  month = aug,
  doi = {10.1016/j.xjon.2026.102079},
  url = {https://europepmc.org/article/MED/42948530},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Saphenous vein grafts from thigh versus calf: Comparison of angiographic patency and clinical outcomes.
AU  - Suk Ho Sohn
AU  - Hee Ju Hong
AU  - Suji Oh
AU  - Yuri Lee
AU  - Yoonjin Kang
AU  - Jae Woong Choi
AU  - Ho Young Hwang
PY  - 2026
DA  - 2026/08/22
JO  - JTCVS open
DO  - 10.1016/j.xjon.2026.102079
UR  - https://europepmc.org/article/MED/42948530
AB  - Objectives  This study compared angiographic patency and clinical outcomes between patients who received saphenous vein (SV) grafts from the upper leg (UL) and those who received grafts from the lower leg (LL) for coronary artery bypass grafting (CABG).Methods  A total of 1630 patients who received primary isolated off-pump CABG using the SV harvested via the no-touch technique from the UL (UL group, n = 203) or the LL (LL group, n = 1427) were enrolled in this study. Propensity score matching was performed, and 202 pairs were matched. Early, 1-year, and 5-year graft angiograms were obtained for 99.5%, 85.7%, and 31.2% of the cohort, respectively. The median follow-up duration was 85.8 months. The primary outcome was midterm angiographic patency, and the secondary outcomes were midterm clinical outcomes.Results  There was no significant difference in baseline characteristics between the matched groups. Early clinical outcomes, including operative mortality (0.8%, 13 out of 1630), demonstrated no intergroup differences. Angiographic patency for SV grafts was not significantly different at early (98.3% vs 98.5% in the UL group vs the LL group, P = .80), 1-year (94.8% vs 95.4% in the UL group vs the LL group, P = .74), or 5-year evaluation (97.8% vs 96.0% in the UL group vs the LL group, P = .43). Midterm survival up to 7 years was comparable between the groups (P = .81).Conclusions  SV grafts from the UL demonstrated comparable 5-year angiographic patency and 7-year clinical outcomes compared with those from the LL during off-pump CABG.
SN  - 2666-2736
ER  -