Association Between the cMIND Diet Pattern, Psychological Resilience and Cognitive Decline Trajectories: Findings from a Prospective Cohort Study in China
- 1Department of Epidemiology and Health Statistics, School of Public Health, Tianjin Medical University, Tianjin 300070, China
- 2Key Laboratory of Prevention and Control of Major Diseases in the Population, Ministry of Education, Tianjin Medical University, Tianjin 300070, China
- 3Department of Clinical Laboratory, Tianjin Medical University General Hospital, Tianjin 300052, China
Abstract
Background: The Chinese version of the Mediterranean–DASH (Dietary Approaches to Stop Hypertension) Intervention for Neurodegenerative Delay (cMIND) diet is hypothesized to slow cognitive decline; nevertheless, most existing evidence is cross-sectional, precluding examination of the longitudinal association between the cMIND diet and heterogeneous cognitive decline trajectories. Moreover, it remains unclear whether psychological resilience mediates this relationship in older Chinese adults. Objectives: We assessed the longitudinal association between cMIND diet adherence and dynamic cognitive trajectories, and evaluated whether psychological resilience mediated the association between the cMIND diet and cognitive trajectories. Methods: Data came from the Chinese Longitudinal Healthy Longevity Survey (CLHLS), a national survey of older adults. cMIND diet scores were grouped into lower (0–4), middle (4.5–5.5), and higher (6–12). A group-based trajectory model (GBTM) was used to identify cognitive decline trajectories. A multinomial logistic regression model was applied to analyse the relationship between the cMIND diet pattern and cognitive decline trajectories in older adults. A mediation analysis was performed on the potential mediating effect of psychological resilience. Results: A total of 1755 participants were included. Participants were divided into three trajectories: the low-level rapid decline trajectory (n = 344, 19.6%), the high-level stable trajectory (n = 551, 31.4%), and the moderate-level slow decline trajectory (n = 860, 49.0%). Compared with the stable trajectory, lower diet scores were associated with the rapid decline cognitive trajectory (OR: 1.59; 95% CI: 1.03, 2.48) and the slow decline cognitive trajectory (OR: 1.61; 95% CI: 1.16, 2.23). The mediating effect of psychological resilience on the relationship between the cMIND diet pattern and cognitive trajectories was not statistically significant (p > 0.05). Conclusions: The cMIND diet pattern was significantly associated with cognitive trajectories in older Chinese adults, with higher adherence associated with stable trajectories and lower adherence associated with rapid and slow decline trajectories. However, psychological resilience did not significantly mediate the relationship between the cMIND diet pattern and cognitive trajectories.
Related
- Prospective associations between perceived school climate and psychological distress among Chinese adolescents: a three-wave longitudinal study of school belonging, social avoidance, and psychological resilience
- Baseline depressive-symptom severity and divergent psychological trajectories during GIP and/or GLP-1 receptor agonist therapy: a prospective ecological momentary assessment study
- Social isolation, self-perceived loneliness, and the 7-year trajectories of depression and cognitive decline: a prospective cohort study
- Latent psychological resilience profiles and their association with physical resilience in older patients after robot-assisted radical prostatectomy: a cross-sectional study
- Trajectories and predictors of psychological distress during the first 6 months of weight loss among adults with obesity: a prospective longitudinal cohort study
BibTeX
@article{zhou2026association,
title = {{Association Between the cMIND Diet Pattern, Psychological Resilience and Cognitive Decline Trajectories: Findings from a Prospective Cohort Study in China}},
author = {Shengjie Zhou and Yuxuan Qi and Ruifang Yang and Jing Yuan and Xian Cai and Wenxue Zhang and Yu Tian and Fei Ma},
journal = {Nutrients},
year = {2026},
month = oct,
doi = {10.3390/nu18213608},
url = {https://www.mdpi.com/2072-6643/18/21/3608},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Association Between the cMIND Diet Pattern, Psychological Resilience and Cognitive Decline Trajectories: Findings from a Prospective Cohort Study in China
AU - Shengjie Zhou
AU - Yuxuan Qi
AU - Ruifang Yang
AU - Jing Yuan
AU - Xian Cai
AU - Wenxue Zhang
AU - Yu Tian
AU - Fei Ma
PY - 2026
DA - 2026/10/30
JO - Nutrients
DO - 10.3390/nu18213608
UR - https://www.mdpi.com/2072-6643/18/21/3608
AB - Background: The Chinese version of the Mediterranean–DASH (Dietary Approaches to Stop Hypertension) Intervention for Neurodegenerative Delay (cMIND) diet is hypothesized to slow cognitive decline; nevertheless, most existing evidence is cross-sectional, precluding examination of the longitudinal association between the cMIND diet and heterogeneous cognitive decline trajectories. Moreover, it remains unclear whether psychological resilience mediates this relationship in older Chinese adults. Objectives: We assessed the longitudinal association between cMIND diet adherence and dynamic cognitive trajectories, and evaluated whether psychological resilience mediated the association between the cMIND diet and cognitive trajectories. Methods: Data came from the Chinese Longitudinal Healthy Longevity Survey (CLHLS), a national survey of older adults. cMIND diet scores were grouped into lower (0–4), middle (4.5–5.5), and higher (6–12). A group-based trajectory model (GBTM) was used to identify cognitive decline trajectories. A multinomial logistic regression model was applied to analyse the relationship between the cMIND diet pattern and cognitive decline trajectories in older adults. A mediation analysis was performed on the potential mediating effect of psychological resilience. Results: A total of 1755 participants were included. Participants were divided into three trajectories: the low-level rapid decline trajectory (n = 344, 19.6%), the high-level stable trajectory (n = 551, 31.4%), and the moderate-level slow decline trajectory (n = 860, 49.0%). Compared with the stable trajectory, lower diet scores were associated with the rapid decline cognitive trajectory (OR: 1.59; 95% CI: 1.03, 2.48) and the slow decline cognitive trajectory (OR: 1.61; 95% CI: 1.16, 2.23). The mediating effect of psychological resilience on the relationship between the cMIND diet pattern and cognitive trajectories was not statistically significant (p > 0.05). Conclusions: The cMIND diet pattern was significantly associated with cognitive trajectories in older Chinese adults, with higher adherence associated with stable trajectories and lower adherence associated with rapid and slow decline trajectories. However, psychological resilience did not significantly mediate the relationship between the cMIND diet pattern and cognitive trajectories.
SN - 2072-6643
ER -