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Peer-reviewedCC BY 4.0Journal of Clinical Medicine

Bleeding Following Frozen Elephant Trunk Surgery: A Proposed Reporting Dataset and Research Agenda

11 affiliations
  1. 1Clinic of Anaesthesia and Intensive Care, Institute for Cardiovascular Diseases of Timișoara, “Victor Babeș” University of Medicine and Pharmacy Timișoara, Gheorghe Adam Street No. 13A, 300310 Timișoara, Romania
  2. 2Department of Doctoral Studies, “Victor Babeș” University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, 300041 Timișoara, Romania
  3. 3Institute for Cardiovascular Diseases of Timișoara, “Victor Babeș” University of Medicine and Pharmacy Timișoara, Gheorghe Adam Street No. 13A, 300310 Timișoara, Romania
  4. 4Doctoral School Medicine-Pharmacy, “Victor Babeș” University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, 300041 Timișoara, Romania
  5. 5Advanced Research Center of the Institute for Cardiovascular Diseases, “Victor Babeș” University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, 300041 Timișoara, Romania
  6. 6Department VI Cardiology-Cardiovascular Surgery, “Victor Babeș” University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, 300041 Timișoara, Romania
  7. 7Department of Doctoral Studies, Faculty of Medicine and Pharmacy, University of Oradea, 1 Universității Street, 410087 Oradea, Romania
  8. 8Department of Surgery X, “Victor Babeș” University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, 300041 Timișoara, Romania
  9. 9Clinic of Cardiovascular Surgery, Institute for Cardiovascular Diseases of Timișoara, Gheorghe Adam Street No. 13A, 300310 Timișoara, Romania
  10. 10Department III Functional Sciences, Pathophysiology, “Victor Babeș” University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, 300041 Timișoara, Romania
  11. 11Centre for Translational Research and Systems Medicine, “Victor Babeș” University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, 300041 Timișoara, Romania

Abstract

Perioperative bleeding after frozen elephant trunk (FET) surgery is reported using heterogeneous endpoints. This structured narrative review examines bleeding sources, measurement and haemostatic management, prioritising recent literature while retaining established landmark definitions. Twelve primary FET clinical publications are tabulated, with technical reports and wider cardiac-surgery evidence providing context. Re-exploration, postoperative drainage, estimated blood loss, transfusion and fabric oozing describe related but distinct phenomena. Established classifications, particularly the Universal Definition of Perioperative Bleeding (UDPB), provide a severity-reporting reference and should not be displaced by a new FET scale. We propose six parallel reporting domains: procedural context; bleeding measurement; haemostatic status; verified source; treatment exposure; and outcomes.. The study-level mapping shows that published FET reports often permit extraction of drainage, re-exploration or treatment exposure, whereas haemostatic status and a directly verified bleeding source are rarely recoverable from published reports. The dataset therefore makes these information gaps explicit and supports prospective evaluation; it does not infer an anatomical source from laboratory findings, drainage or treatment. The proposed reporting dataset is not a validated severity scale or treatment algorithm.

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BibTeX
@article{staicu2026bleeding,
  title = {{Bleeding Following Frozen Elephant Trunk Surgery: A Proposed Reporting Dataset and Research Agenda}},
  author = {Raluca Elisabeta Staicu and Andrei Raul Manzur and Marciana Ionela Boca and Alina-Ramona Cozlac and Andrea Pop-Crisan and Petru Deutsch and Ana Lascu},
  journal = {Journal of Clinical Medicine},
  year = {2026},
  month = nov,
  doi = {10.3390/jcm15218689},
  url = {https://www.mdpi.com/2077-0383/15/21/8689},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Bleeding Following Frozen Elephant Trunk Surgery: A Proposed Reporting Dataset and Research Agenda
AU  - Raluca Elisabeta Staicu
AU  - Andrei Raul Manzur
AU  - Marciana Ionela Boca
AU  - Alina-Ramona Cozlac
AU  - Andrea Pop-Crisan
AU  - Petru Deutsch
AU  - Ana Lascu
PY  - 2026
DA  - 2026/11/07
JO  - Journal of Clinical Medicine
DO  - 10.3390/jcm15218689
UR  - https://www.mdpi.com/2077-0383/15/21/8689
AB  - Perioperative bleeding after frozen elephant trunk (FET) surgery is reported using heterogeneous endpoints. This structured narrative review examines bleeding sources, measurement and haemostatic management, prioritising recent literature while retaining established landmark definitions. Twelve primary FET clinical publications are tabulated, with technical reports and wider cardiac-surgery evidence providing context. Re-exploration, postoperative drainage, estimated blood loss, transfusion and fabric oozing describe related but distinct phenomena. Established classifications, particularly the Universal Definition of Perioperative Bleeding (UDPB), provide a severity-reporting reference and should not be displaced by a new FET scale. We propose six parallel reporting domains: procedural context; bleeding measurement; haemostatic status; verified source; treatment exposure; and outcomes.. The study-level mapping shows that published FET reports often permit extraction of drainage, re-exploration or treatment exposure, whereas haemostatic status and a directly verified bleeding source are rarely recoverable from published reports. The dataset therefore makes these information gaps explicit and supports prospective evaluation; it does not infer an anatomical source from laboratory findings, drainage or treatment. The proposed reporting dataset is not a validated severity scale or treatment algorithm.
SN  - 2077-0383
ER  -