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Peer-reviewedCC BYOncoImmunology

Restoring dendritic cell migration: a gut reaction to boost vaccine efficacy in aging

  • Liwei Zhao
  • Oliver Kepp
  • Guido Kroemer
  • Peng Liu
Open at sourcePDFDOICite

Abstract

Aging impairs vaccine responses. Dai et al. reported that defective cDC2 migration in immunized old mice, diminishing humoral and cellular immunity. Oral yeast-derived nanoparticles restore DC migration and vaccine efficacy. These findings establish impaired DC migration as a key mechanism of age-related immune decline, introducing a noninvasive strategy to correct immunosenescence.

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Cite

BibTeXRIS
BibTeX
@article{zhao2026restoring,
  title = {{Restoring dendritic cell migration: a gut reaction to boost vaccine efficacy in aging}},
  author = {Liwei Zhao and Oliver Kepp and Guido Kroemer and Peng Liu},
  journal = {OncoImmunology},
  year = {2026},
  month = sep,
  doi = {10.1080/2162402x.2026.2657070},
  url = {https://hal.science/hal-05772117v1},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Restoring dendritic cell migration: a gut reaction to boost vaccine efficacy in aging
AU  - Liwei Zhao
AU  - Oliver Kepp
AU  - Guido Kroemer
AU  - Peng Liu
PY  - 2026
DA  - 2026/09/30
JO  - OncoImmunology
DO  - 10.1080/2162402x.2026.2657070
UR  - https://hal.science/hal-05772117v1
AB  - Aging impairs vaccine responses. Dai et al. reported that defective cDC2 migration in immunized old mice, diminishing humoral and cellular immunity. Oral yeast-derived nanoparticles restore DC migration and vaccine efficacy. These findings establish impaired DC migration as a key mechanism of age-related immune decline, introducing a noninvasive strategy to correct immunosenescence.
SN  - 2162-4011
SN  - 2162-402X
ER  -