Management of renal failure in earthquake-related crush syndrome: Multicenter intensive care outcomes.

@article{hatipoglu2026management,
  title = {{Management of renal failure in earthquake-related crush syndrome: Multicenter intensive care outcomes.}},
  author = {Zehra Hatipoğlu and Ömer Doğan and Mehmet Gökhan Gök and Kaniye Aydın and Ersel Güleç and Mediha Türktan and Ferhat Çetinkaya and Eda Macit Aydın and Büşra Tezcan and Murat Sayın and Ahu Dudu Akarca and Didem Sözütek and Devrim Söğüt Akdağ and Sinem Bayrakçı and Nazire Ateş Ayhan and İlhan Asude Ağahan and Gamze Koçak and Nihal Deniz Bulut Yüksel and Deniz Yüksel and Ahmet Coşar and Hatice Yağmurdur and Tülay Tuncer Peker and Nilgün Kavrut Öztürk and Vecihe Bayrak and Sedat Kaya and Aliye Esmaoğlu and Nuray Altay and Serhat Atılgan and Yeşim Şerife Bayraktar and Hilal Sipahioğlu and Kamuran Uluç and Yusuf Kemal Arslan and Dilek Özcengiz},
  journal = {Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma \& emergency surgery : TJTES},
  year = {2026},
  month = oct,
  doi = {10.14744/tjtes.2026.66645},
  url = {https://europepmc.org/article/MED/42841896},
  note = {CC BY-NC},
}

TY  - JOUR
TI  - Management of renal failure in earthquake-related crush syndrome: Multicenter intensive care outcomes.
AU  - Zehra Hatipoğlu
AU  - Ömer Doğan
AU  - Mehmet Gökhan Gök
AU  - Kaniye Aydın
AU  - Ersel Güleç
AU  - Mediha Türktan
AU  - Ferhat Çetinkaya
AU  - Eda Macit Aydın
AU  - Büşra Tezcan
AU  - Murat Sayın
AU  - Ahu Dudu Akarca
AU  - Didem Sözütek
AU  - Devrim Söğüt Akdağ
AU  - Sinem Bayrakçı
AU  - Nazire Ateş Ayhan
AU  - İlhan Asude Ağahan
AU  - Gamze Koçak
AU  - Nihal Deniz Bulut Yüksel
AU  - Deniz Yüksel
AU  - Ahmet Coşar
AU  - Hatice Yağmurdur
AU  - Tülay Tuncer Peker
AU  - Nilgün Kavrut Öztürk
AU  - Vecihe Bayrak
AU  - Sedat Kaya
AU  - Aliye Esmaoğlu
AU  - Nuray Altay
AU  - Serhat Atılgan
AU  - Yeşim Şerife Bayraktar
AU  - Hilal Sipahioğlu
AU  - Kamuran Uluç
AU  - Yusuf Kemal Arslan
AU  - Dilek Özcengiz
PY  - 2026
DA  - 2026/10/01
JO  - Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES
DO  - 10.14744/tjtes.2026.66645
UR  - https://europepmc.org/article/MED/42841896
AB  - Background  Crush syndrome (CS) is a clinical condition associated with multisystem organ dysfunction that develops after traumatic rhabdomyolysis and primarily affects the kidneys. The aim of this study was to characterize the incidence, risk factors, and treatment patterns of acute kidney injury (AKI) in earthquake victims with CS, with a particular focus on renal replacement therapy (RRT) use and clinical outcomes.Methods  In this retrospective multicenter study, 247 adult patients with earthquake-related CS who were admitted to intensive care units (ICUs) in 22 hospitals after the Kahramanmaraş 2023 earthquakes were analyzed. Demographic data, injury patterns, laboratory parameters, treatment protocols, and outcomes were evaluated during the first 15 days following ICU admission.Results  AKI developed in 78.5% (n=194) of patients, and RRT was required in 62.4% (n=121) of those with AKI. Multiple logistic regression analysis demonstrated that myoglobin and creatinine levels were associated with an elevated risk of developing AKI (odds ratio [OR]: 1.001; 95% confidence interval CI: 1.000-1.001 and OR: 1.735; 95% CI: 1.151-2.615, respectively). Similarly, creatinine level and reasons for ICU admission were identified as factors influencing RRT administration. (OR: 1.7; 95% CI: 1.28-2.15 and OR: 2.9; 95% CI: 1.26-6.90, respectively). The 30-day mortality rate was higher in patients with AKI than in those without AKI. Mortality rates were similar between patients with AKI who received RRT and those who did not.Conclusion  This study demonstrates the high incidence of AKI in earthquake-related CS, underscores the need for improved disaster preparedness with adequate dialysis capacity and early risk stratification using serum myoglobin and creatinine levels for optimal management.
SN  - 1306-696X
SN  - 1307-7945
ER  -