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Peer-reviewedCC BYMicroPublication biology

The nonsense mutation of the smu-1(mn415) allele is in exon 6 at Q257, not in exon 5 at Q255.

  • Nirmala Devi Rajendra Chauhan1
  • Timothy Pearson1
  • Alper Akay1
  1. 1School of Biological Sciences, University of East Anglia, Norwich, ENG, United Kingdom.
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Abstract

smu-1 encodes the Caenorhabditis elegans orthologue of the spliceosomal protein SMU1. The smu-1 ( mn415 ) allele was originally identified as a suppressor of synthetic lethality between mec-8 and unc-52 and was mapped to a stop codon at amino acid position 255 in exon 5. Our Sanger sequencing analysis of the smu-1 ( mn415 ) allele shows that the stop codon is at amino acid position 257 in exon 6.

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Cite

BibTeXRIS
BibTeX
@article{chauhan2026nonsense,
  title = {{The nonsense mutation of the smu-1(mn415) allele is in exon 6 at Q257, not in exon 5 at Q255.}},
  author = {Nirmala Devi Rajendra Chauhan and Timothy Pearson and Alper Akay},
  journal = {MicroPublication biology},
  year = {2026},
  month = oct,
  doi = {10.17912/micropub.biology.002454},
  url = {https://europepmc.org/article/MED/42997208},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - The nonsense mutation of the smu-1(mn415) allele is in exon 6 at Q257, not in exon 5 at Q255.
AU  - Nirmala Devi Rajendra Chauhan
AU  - Timothy Pearson
AU  - Alper Akay
PY  - 2026
DA  - 2026/10/22
JO  - MicroPublication biology
DO  - 10.17912/micropub.biology.002454
UR  - https://europepmc.org/article/MED/42997208
AB  - smu-1 encodes the Caenorhabditis elegans orthologue of the spliceosomal protein SMU1. The smu-1 ( mn415 ) allele was originally identified as a suppressor of synthetic lethality between mec-8 and unc-52 and was mapped to a stop codon at amino acid position 255 in exon 5. Our Sanger sequencing analysis of the smu-1 ( mn415 ) allele shows that the stop codon is at amino acid position 257 in exon 6.
SN  - 2578-9430
ER  -