Effects of Nutritional Guidance on Acute Myocardial Infarction: A Retrospective Cohort Study
Abstract
AIM: This retrospective cohort study aimed to investigate the impact of nutritionist-led dietary guidance on the prognosis of patients with acute myocardial infarction (AMI). METHODS: The cohort encompassed 446 consecutive patients with AMI in a single center who underwent emergency coronary angiography and percutaneous coronary interventions from September 1, 2015 to October 31, 2023. RESULTS: Based on defined caloric intake and macronutrient ratios, 54.7% of the patients received nutritional guidance during hospitalization. During a 39-month median follow-up, this study documented 24 (5.9%) and 6 (1.5%) cases of all-cause and cardiovascular mortality, respectively. Furthermore, among the components of the primary composite endpoint, 15 (3.7%), 17 (4.2%), and 20 (4.9%) cases of nonfatal stroke, nonfatal acute coronary syndrome, and hospitalizations for acute decompensated heart failure, respectively, were noted. Kaplan-Meier curves demonstrated that patients without nutritional guidance showed significantly higher incidence rates of mortality and primary composite endpoints. Considering multiple variables, the multivariate Cox regression model identified nutritional guidance as a significant predictor for long-term mortality but not for primary composite endpoints. Patients receiving nutritional guidance exhibited significantly improved albumin and C-reactive protein levels, with a trend toward better survival rate. CONCLUSION: This study suggests that by addressing dietary factors influencing inflammation and lipid metabolism, structured nutritional guidance can enhance prognosis in patients with AMI. To delineate the dietary components most beneficial for patients with AMI, further research is warranted.
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BibTeX
@article{abe2026effects,
title = {{Effects of Nutritional Guidance on Acute Myocardial Infarction: A Retrospective Cohort Study}},
author = {Hiroshi Abe and Tetsuro Miyazaki and Takamasa Suzuki and Mari Sumiyoshi and Tomaru Masato and Midori Kakihara and Masaaki Maki and Ryosuke Shimai and Hiroyuki Isogai and Dai Ozaki and Yuki Yasuda and Fuminori Odagiri and Kiyoshi Takasu and Kazuhisa Takamura and Makoto Hiki and Takashi Tokano and Tohru Minamino},
journal = {Journal of Atherosclerosis and Thrombosis},
year = {2026},
month = jul,
doi = {10.5551/jat.66235},
url = {https://www.jstage.jst.go.jp/article/jat/advpub/0/advpub_66235/_article},
note = {CC BY-NC-SA},
}
RIS
TY - JOUR
TI - Effects of Nutritional Guidance on Acute Myocardial Infarction: A Retrospective Cohort Study
AU - Hiroshi Abe
AU - Tetsuro Miyazaki
AU - Takamasa Suzuki
AU - Mari Sumiyoshi
AU - Tomaru Masato
AU - Midori Kakihara
AU - Masaaki Maki
AU - Ryosuke Shimai
AU - Hiroyuki Isogai
AU - Dai Ozaki
AU - Yuki Yasuda
AU - Fuminori Odagiri
AU - Kiyoshi Takasu
AU - Kazuhisa Takamura
AU - Makoto Hiki
AU - Takashi Tokano
AU - Tohru Minamino
PY - 2026
DA - 2026/07/24
JO - Journal of Atherosclerosis and Thrombosis
DO - 10.5551/jat.66235
UR - https://www.jstage.jst.go.jp/article/jat/advpub/0/advpub_66235/_article
AB - AIM: This retrospective cohort study aimed to investigate the impact of nutritionist-led dietary guidance on the prognosis of patients with acute myocardial infarction (AMI). METHODS: The cohort encompassed 446 consecutive patients with AMI in a single center who underwent emergency coronary angiography and percutaneous coronary interventions from September 1, 2015 to October 31, 2023. RESULTS: Based on defined caloric intake and macronutrient ratios, 54.7% of the patients received nutritional guidance during hospitalization. During a 39-month median follow-up, this study documented 24 (5.9%) and 6 (1.5%) cases of all-cause and cardiovascular mortality, respectively. Furthermore, among the components of the primary composite endpoint, 15 (3.7%), 17 (4.2%), and 20 (4.9%) cases of nonfatal stroke, nonfatal acute coronary syndrome, and hospitalizations for acute decompensated heart failure, respectively, were noted. Kaplan-Meier curves demonstrated that patients without nutritional guidance showed significantly higher incidence rates of mortality and primary composite endpoints. Considering multiple variables, the multivariate Cox regression model identified nutritional guidance as a significant predictor for long-term mortality but not for primary composite endpoints. Patients receiving nutritional guidance exhibited significantly improved albumin and C-reactive protein levels, with a trend toward better survival rate. CONCLUSION: This study suggests that by addressing dietary factors influencing inflammation and lipid metabolism, structured nutritional guidance can enhance prognosis in patients with AMI. To delineate the dietary components most beneficial for patients with AMI, further research is warranted.
SN - 1880-3873
SN - 1340-3478
ER -