Skip to content
DraconiticResearch
Search Sources API
203,234 studies31 sourcesUpdated 4 min ago
Peer-reviewedCC BY-NCJournal of clinical hypertension (Greenwich, Conn.)

Perinatal Factors Associated With Standardized Blood Pressure Percentiles for Children Aged 6 to 12 Years: The BOSHI Study

  • Hiroki Nobayashi1
  • Seiya Izumi2
  • Michihiro Satoh1
  • Noriyuki Iwama3
  • Takahisa Murakami1
  • Go Kanzaki4
  • Yutaro Iwabe1
  • Yuya Suzuki1
  • Mami Ishikuro5
  • Nobuo Tsuboi4
  • Taku Obara5
  • Takayoshi Ohkubo6
2 more authors
  • Takashi Yokoo4
  • Hirohito Metoki1
6 affiliations
  1. 1Tohoku Medical and Pharmaceutical University
  2. 2Tohoku University Graduate School of Medicine
  3. 3Tohoku University Hospital
  4. 4The Jikei University School of Medicine
  5. 5Tohoku University
  6. 6Teikyo University School of Medicine
Read full textPDFDOICite

Abstract

Elevated childhood blood pressure (BP) is associated with adulthood cardiovascular mortality. However, evidence of an association between maternal and perinatal factors and standardized childhood BP percentiles in Japan remains limited. In this study, we examined this association by using data from the BOSHI study, which included children's home BP measurements. Among 175 mother–offspring pairs, the mean maternal age and children's birth weight were 32.4 years and 3031 g, respectively; the median age of the children at follow‐up was 7 years; and hypertensive disorders of pregnancy occurred in 43 mothers. Multivariable analyses showed that higher birth weight was associated with lower diastolic BP percentiles (−0.87 percentile per 100‐g increase; p = 0.03). Given previous evidence linking elevated childhood BP to subsequent cardiovascular risk later in life, our findings warrant further investigation in diverse populations.

Related

  1. Beyond Perinatal Mood: Breadth of Psychiatric Symptoms and Delay Discounting as Correlates of Mothers' Relational Reports from Pregnancy Through Adult Children
    R. DeLauder, M. Hebert, S. Rhodes +5
    medRxivPreprintAll rights reservedFull textPsychiatry & mental healthmedRxiv
  2. Early BMI-associated increases in central and peripheral blood pressure in primary school children: evidence of a continuous, nonlinear relationship below the overweight threshold.
    Jeannine von der Born, Lisa Wilmsmeier, Rizky I Sugianto +9
    European journal of pediatricsPeer-reviewedCC BYFull textEpidemiology & public healthEurope PMCPMC
  3. High rates of obesity and excessive catch-up growth in children with perinatal HIV exposure in the United States
    Denise L. Jacobson, Wendy Yu, Mitchell Geffner +11
    Journal of acquired immune deficiency syndromes (1999)Peer-reviewedLicence not statedFull textInfectious diseasePMC
  4. Reply-Letter to the editor. Nutritional Goals in Mechanically Ventilated Children: Impact of a Standardized Enteral Protocol in a Tertiary Pediatric Intensive Care Unit
    Arthur Gaudaire, Cyril Ceci, Héléna Huguet +7
    Clinical Nutrition ESPENPeer-reviewedCC BY 4.0Full textGeneral biologyEpidemiology & public healthHAL
  5. Perinatal and gestational factors associated with Pavlik harness outcomes in developmental dysplasia of the hip: a retrospective cohort study
    Xinyue Liang, Boyuan Ma, Rong Li +4
    Frontiers in pediatricsPeer-reviewedCC BYFull textGeneral medicineEurope PMC

Cite

BibTeXRIS
BibTeX
@article{nobayashi2026perinatal,
  title = {{Perinatal Factors Associated With Standardized Blood Pressure Percentiles for Children Aged 6 to 12 Years: The BOSHI Study}},
  author = {Hiroki Nobayashi and Seiya Izumi and Michihiro Satoh and Noriyuki Iwama and Takahisa Murakami and Go Kanzaki and Yutaro Iwabe and Yuya Suzuki and Mami Ishikuro and Nobuo Tsuboi and Taku Obara and Takayoshi Ohkubo and Takashi Yokoo and Hirohito Metoki},
  journal = {Journal of clinical hypertension (Greenwich, Conn.)},
  year = {2026},
  month = oct,
  doi = {10.1111/jch.70376},
  url = {https://europepmc.org/article/PMC/PMC13657260},
  note = {CC BY-NC},
}
RIS
TY  - JOUR
TI  - Perinatal Factors Associated With Standardized Blood Pressure Percentiles for Children Aged 6 to 12 Years: The BOSHI Study
AU  - Hiroki Nobayashi
AU  - Seiya Izumi
AU  - Michihiro Satoh
AU  - Noriyuki Iwama
AU  - Takahisa Murakami
AU  - Go Kanzaki
AU  - Yutaro Iwabe
AU  - Yuya Suzuki
AU  - Mami Ishikuro
AU  - Nobuo Tsuboi
AU  - Taku Obara
AU  - Takayoshi Ohkubo
AU  - Takashi Yokoo
AU  - Hirohito Metoki
PY  - 2026
DA  - 2026/10/01
JO  - Journal of clinical hypertension (Greenwich, Conn.)
DO  - 10.1111/jch.70376
UR  - https://europepmc.org/article/PMC/PMC13657260
AB  - Elevated childhood blood pressure (BP) is associated with adulthood cardiovascular mortality. However, evidence of an association between maternal and perinatal factors and standardized childhood BP percentiles in Japan remains limited. In this study, we examined this association by using data from the BOSHI study, which included children's home BP measurements. Among 175 mother–offspring pairs, the mean maternal age and children's birth weight were 32.4 years and 3031 g, respectively; the median age of the children at follow‐up was 7 years; and hypertensive disorders of pregnancy occurred in 43 mothers. Multivariable analyses showed that higher birth weight was associated with lower diastolic BP percentiles (−0.87 percentile per 100‐g increase; p = 0.03). Given previous evidence linking elevated childhood BP to subsequent cardiovascular risk later in life, our findings warrant further investigation in diverse populations.
SN  - 1524-6175
SN  - 1751-7176
ER  -