Assessing the utility of two sarcopenia screening tools in predicting mortality risk among survivors of critical illness: a single-center study
- 1Department of Emergency, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, People’s Hospital of Henan University
- 2Department of General Surgery, Affiliated Xiaoshan Hospital, Hangzhou Normal University
- 3Department of Nephrology, The Second Affiliated Hospital of Hainan Medical University
Abstract
Older survivors of critical illness often have reduced muscle reserve and functional impairment, but practical tools for identifying sarcopenia risk at clinically relevant time points remain uncertain. This prospective single-center study included 483 ICU survivors aged ≥ 60 years. Sarcopenia risk was assessed using the SARC-CalF score within 24 h of ICU admission and the Ishii score at ICU discharge. The primary outcomes were 30-day and 365-day all-cause mortality after hospital discharge, with observed mortality rates of 9.3% and 23.8%, respectively. In multivariable models adjusted for age, sex, APACHE II, Charlson Comorbidity Index, and Clinical Frailty Scale, both scores were independently associated with 30-day and 365-day mortality. Adding either score to the base model provided incremental prognostic information mainly for 365-day mortality, whereas the improvement for 30-day mortality was limited and not statistically significant for discrimination.These findings suggest that SARC-CalF at ICU admission and Ishii score at ICU discharge are feasible, noninvasive screening tools for identifying older ICU survivors at increased mortality risk—and could help inform post-ICU risk stratification and targeted rehabilitation planning.
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BibTeX
@article{chen2026assessing,
title = {{Assessing the utility of two sarcopenia screening tools in predicting mortality risk among survivors of critical illness: a single-center study}},
author = {Long Chen and Juan Xu and Raoman Feng and Weimin Bai},
journal = {Scientific Reports},
year = {2026},
month = jul,
doi = {10.1038/s41598-026-63220-9},
url = {https://doi.org/10.1038/s41598-026-63220-9},
note = {CC BY},
}
RIS
TY - JOUR
TI - Assessing the utility of two sarcopenia screening tools in predicting mortality risk among survivors of critical illness: a single-center study
AU - Long Chen
AU - Juan Xu
AU - Raoman Feng
AU - Weimin Bai
PY - 2026
DA - 2026/07/01
JO - Scientific Reports
DO - 10.1038/s41598-026-63220-9
UR - https://doi.org/10.1038/s41598-026-63220-9
AB - Older survivors of critical illness often have reduced muscle reserve and functional impairment, but practical tools for identifying sarcopenia risk at clinically relevant time points remain uncertain. This prospective single-center study included 483 ICU survivors aged ≥ 60 years. Sarcopenia risk was assessed using the SARC-CalF score within 24 h of ICU admission and the Ishii score at ICU discharge. The primary outcomes were 30-day and 365-day all-cause mortality after hospital discharge, with observed mortality rates of 9.3% and 23.8%, respectively. In multivariable models adjusted for age, sex, APACHE II, Charlson Comorbidity Index, and Clinical Frailty Scale, both scores were independently associated with 30-day and 365-day mortality. Adding either score to the base model provided incremental prognostic information mainly for 365-day mortality, whereas the improvement for 30-day mortality was limited and not statistically significant for discrimination.These findings suggest that SARC-CalF at ICU admission and Ishii score at ICU discharge are feasible, noninvasive screening tools for identifying older ICU survivors at increased mortality risk—and could help inform post-ICU risk stratification and targeted rehabilitation planning.
SN - 2045-2322
ER -