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Peer-reviewedCC BYAdvances in ophthalmology practice and research

Lens capsule-related complications in cataract phacoemulsification: Advances in pathophysiology and clinical management.

  • Qian Luo1,2
  • Lei Yang2
  • Xiangbin Guan1,2
  • Furong Liao2
  • Li Jiang2
  • Yumeng Bao2
  • Jingyi Zhu1,2
  • Yanping Song2
  1. 1Medical College, Wuhan University of Science and Technology, Wuhan, China.
  2. 2Department of Ophthalmology, General Hospital of Central Theater Command of People's Liberation Army, Wuhan, China.
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Abstract

Background

Phacoemulsification surgery is one of the most widely performed ophthalmic procedures for cataract treatment worldwide, and the occurrence of lens capsule-related complications has a significant impact on surgical outcomes and visual prognosis of patients.Main text

In this review article, we focus on lens capsule-related complications, including posterior capsule rupture, anterior capsular tear, capsule bend, anterior and posterior capsule opacification, capsular bag distension syndrome, capsular contraction syndrome, and dead bag syndrome. Drawing on both basic research and clinical evidence, we provide an updated overview of current evidence regarding their underlying mechanisms and key clinical treatment strategies. The risk factors for the occurrence of various complications are explored. The core pathophysiological mechanisms, including changes in capsule biomechanics, as well as the proliferation, migration, and fibrosis of lens epithelial cells, are analyzed in detail.Conclusions

Based on the above analysis, we summarize prevention and management strategies in hopes of improving the safety and effectiveness of cataract surgery.

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Cite

BibTeXRIS
BibTeX
@article{luo2026lens,
  title = {{Lens capsule-related complications in cataract phacoemulsification: Advances in pathophysiology and clinical management.}},
  author = {Qian Luo and Lei Yang and Xiangbin Guan and Furong Liao and Li Jiang and Yumeng Bao and Jingyi Zhu and Yanping Song},
  journal = {Advances in ophthalmology practice and research},
  year = {2026},
  month = may,
  doi = {10.1016/j.aopr.2026.05.002},
  url = {https://europepmc.org/article/MED/42927231},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Lens capsule-related complications in cataract phacoemulsification: Advances in pathophysiology and clinical management.
AU  - Qian Luo
AU  - Lei Yang
AU  - Xiangbin Guan
AU  - Furong Liao
AU  - Li Jiang
AU  - Yumeng Bao
AU  - Jingyi Zhu
AU  - Yanping Song
PY  - 2026
DA  - 2026/05/14
JO  - Advances in ophthalmology practice and research
DO  - 10.1016/j.aopr.2026.05.002
UR  - https://europepmc.org/article/MED/42927231
AB  - Background  Phacoemulsification surgery is one of the most widely performed ophthalmic procedures for cataract treatment worldwide, and the occurrence of lens capsule-related complications has a significant impact on surgical outcomes and visual prognosis of patients.Main text  In this review article, we focus on lens capsule-related complications, including posterior capsule rupture, anterior capsular tear, capsule bend, anterior and posterior capsule opacification, capsular bag distension syndrome, capsular contraction syndrome, and dead bag syndrome. Drawing on both basic research and clinical evidence, we provide an updated overview of current evidence regarding their underlying mechanisms and key clinical treatment strategies. The risk factors for the occurrence of various complications are explored. The core pathophysiological mechanisms, including changes in capsule biomechanics, as well as the proliferation, migration, and fibrosis of lens epithelial cells, are analyzed in detail.Conclusions  Based on the above analysis, we summarize prevention and management strategies in hopes of improving the safety and effectiveness of cataract surgery.
SN  - 2667-3762
ER  -