Endoscopic third ventriculostomy for management of vein of Galen aneurysmal malformation-associated hydrocephalus with spontaneous thrombosis: case report.
- 1Department of Neurosurgery, Children's National Hospital, Washington, DC, United States.
Abstract
Vein of Galen aneurysmal malformations (VGAMs) are rare cerebrovascular anomalies due to lack of involution of the prosencephalic vein of Markowski in early gestation. Children born with such pathology may present with high-output cardiac failure, developmental delay, seizures, and hydrocephalus (Lasjaunias et al., 2006; Berenstein et al., 2010). Hydrocephalus may present due to aqueductal obstruction, intraventricular hemorrhage, or venous hypertension leading to absorptive deficit. Historical data suggests extremely high rates of complications associated with ventriculoperitoneal shunting when required in VGAM (Jea et al., 2010). Herein, we describe our experience with endoscopic third ventriculostomy for treatment of a partially embolized VGAM patient presenting with acute decline secondary to headaches, vomiting, and papilledema with evidence of symptomatic and radiographic resolution at two-month followup. Six-month MRI/MRA followup confirms persistent obliteration of the cerebrovascular lesion.
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BibTeX
@article{naeem2026endoscopic,
title = {{Endoscopic third ventriculostomy for management of vein of Galen aneurysmal malformation-associated hydrocephalus with spontaneous thrombosis: case report.}},
author = {Arhum Naeem and Kelsi Chesney and Sebastian Salas-Vega and Dallas Soyland and Saige A Teti and Sonora Q Robles and Brannan ONeill and Daniel Donoho and Hasan R Syed and Chima O Oluigbo and John S Myseros and Robert F Keating and Kyle Spagnolo and Jonathan Murnick and Monica Pearl and Abdullah H Feroze},
journal = {Frontiers in pediatrics},
year = {2026},
month = oct,
doi = {10.3389/fped.2026.1974046},
url = {https://europepmc.org/article/MED/42908913},
note = {CC BY},
}
RIS
TY - JOUR
TI - Endoscopic third ventriculostomy for management of vein of Galen aneurysmal malformation-associated hydrocephalus with spontaneous thrombosis: case report.
AU - Arhum Naeem
AU - Kelsi Chesney
AU - Sebastian Salas-Vega
AU - Dallas Soyland
AU - Saige A Teti
AU - Sonora Q Robles
AU - Brannan ONeill
AU - Daniel Donoho
AU - Hasan R Syed
AU - Chima O Oluigbo
AU - John S Myseros
AU - Robert F Keating
AU - Kyle Spagnolo
AU - Jonathan Murnick
AU - Monica Pearl
AU - Abdullah H Feroze
PY - 2026
DA - 2026/10/07
JO - Frontiers in pediatrics
DO - 10.3389/fped.2026.1974046
UR - https://europepmc.org/article/MED/42908913
AB - Vein of Galen aneurysmal malformations (VGAMs) are rare cerebrovascular anomalies due to lack of involution of the prosencephalic vein of Markowski in early gestation. Children born with such pathology may present with high-output cardiac failure, developmental delay, seizures, and hydrocephalus (Lasjaunias et al., 2006; Berenstein et al., 2010). Hydrocephalus may present due to aqueductal obstruction, intraventricular hemorrhage, or venous hypertension leading to absorptive deficit. Historical data suggests extremely high rates of complications associated with ventriculoperitoneal shunting when required in VGAM (Jea et al., 2010). Herein, we describe our experience with endoscopic third ventriculostomy for treatment of a partially embolized VGAM patient presenting with acute decline secondary to headaches, vomiting, and papilledema with evidence of symptomatic and radiographic resolution at two-month followup. Six-month MRI/MRA followup confirms persistent obliteration of the cerebrovascular lesion.
SN - 2296-2360
ER -