Nicotine pouch use for smoking cessation in Great Britain: real-world effectiveness, trends, and user characteristics, 2021-2026
- 1UCL
Abstract
ObjectiveTo examine trends in use of nicotine pouches as a smoking cessation aid, characteristics of people using pouches during smoking quit attempts, the characteristics of quit attempts involving pouches, and the real-world association between pouch use and quit success.
DesignMonthly cross-sectional survey.
SettingGreat Britain.
Participants7,995 adults ([≥]18 years) who reported making a serious attempt to stop smoking in the past year, surveyed between June 2021 and July 2026.
Main outcome measuresParticipants reported use of nicotine pouches during the most recent smoking quit attempt (yes/no). Quit success was defined as reporting that the participant was still not smoking following the attempt. Associations between pouch use and quit success were estimated using logistic regression, adjusting for sociodemographic characteristics, use of other cessation aids, characteristics of the quit attempt, strength of urges to smoke, and survey year.
ResultsAmong adults who attempted to quit smoking, the proportion using pouches as a cessation aid increased from 2.4% [95%CI 1.3-4.1%] in June 2021 to 6.7% [4.6-9.6%] in July 2026 (prevalence ratio [PR]=2.83 [1.37-5.81]), with particularly large increases among 18-24-year-olds (2.2% to 18.9%; PR=8.75 [4.15-26.79]) and men (1.8% to 11.0%; PR=6.05 [3.19-14.31]). In 2024-26, 43.8% of those using pouches as a cessation aid were aged 18-24 and 69.5% were men. Pouch users also commonly reported using e-cigarettes (49.6%) or over-the-counter nicotine replacement therapy (37.9%) during the same quit attempt. Unadjusted quit success was 33.5% [27.1-39.9] among pouch users compared with 27.0% [25.9-28.1] among those who did not use pouches (OR=1.36 [1.02-1.82]). After adjustment, the association was attenuated (ORadj=1.15 [0.80-1.65]), with the 95%CI compatible with both a modest adverse association and a modest to large benefit. The association differed according to concurrent e-cigarette use (pinteraction=0.002): among those not using e-cigarettes as a cessation aid, pouch use was associated with higher quit success (ORadj=1.91 [1.23-2.97]), whereas evidence of an association among e-cigarette users was uncertain (ORadj=0.63 [0.36-1.11]).
ConclusionsUse of nicotine pouches as a smoking cessation aid increased substantially in Great Britain between 2021 and 2026, particularly among younger adults and men. Pouches were frequently used alongside other cessation aids. While the overall association with quit success was uncertain, pouch use was associated with higher quit success among those not using e-cigarettes. If causal, this suggests a potential role for pouches among people not already using an established cessation aid.
Related
- A Randomized Factorial Trial of Varenicline, Nicotine Lozenges, and Smartphone Medication Adherence Reminders for Smoking Cessation: Protocol for the COMBO II Study.
- Safety and Effectiveness of Bupropion for Smoking Cessation During Pregnancy: A Scoping Review.
- Rates of oral nicotine pouch experimentation, initiation, and cessation by other tobacco product use and sociodemographic characteristics among U.S. adults, 2022-2024
- Nicotine: evolution, dependence, and the path to total quit: redefining cessation in a changing nicotine landscape
- Nicotine replacement therapy sampling for cigarette cessation in dental care: A National Dental Practice-Based Research Network cluster randomized clinical trial
BibTeX
@misc{jackson2026nicotine,
title = {{Nicotine pouch use for smoking cessation in Great Britain: real-world effectiveness, trends, and user characteristics, 2021-2026}},
author = {S. E. Jackson and H. Tattan-Birch and H. Sun and S. Cox and M. Oldham and J. Brown},
howpublished = {medRxiv},
year = {2026},
month = oct,
doi = {10.64898/2026.10.21.26366107},
url = {https://www.medrxiv.org/content/10.64898/2026.10.21.26366107v1},
note = {CC BY},
}
RIS
TY - UNPB
TI - Nicotine pouch use for smoking cessation in Great Britain: real-world effectiveness, trends, and user characteristics, 2021-2026
AU - S. E. Jackson
AU - H. Tattan-Birch
AU - H. Sun
AU - S. Cox
AU - M. Oldham
AU - J. Brown
PY - 2026
DA - 2026/10/21
PB - medRxiv
DO - 10.64898/2026.10.21.26366107
UR - https://www.medrxiv.org/content/10.64898/2026.10.21.26366107v1
AB - ObjectiveTo examine trends in use of nicotine pouches as a smoking cessation aid, characteristics of people using pouches during smoking quit attempts, the characteristics of quit attempts involving pouches, and the real-world association between pouch use and quit success. DesignMonthly cross-sectional survey. SettingGreat Britain. Participants7,995 adults ([≥]18 years) who reported making a serious attempt to stop smoking in the past year, surveyed between June 2021 and July 2026. Main outcome measuresParticipants reported use of nicotine pouches during the most recent smoking quit attempt (yes/no). Quit success was defined as reporting that the participant was still not smoking following the attempt. Associations between pouch use and quit success were estimated using logistic regression, adjusting for sociodemographic characteristics, use of other cessation aids, characteristics of the quit attempt, strength of urges to smoke, and survey year. ResultsAmong adults who attempted to quit smoking, the proportion using pouches as a cessation aid increased from 2.4% [95%CI 1.3-4.1%] in June 2021 to 6.7% [4.6-9.6%] in July 2026 (prevalence ratio [PR]=2.83 [1.37-5.81]), with particularly large increases among 18-24-year-olds (2.2% to 18.9%; PR=8.75 [4.15-26.79]) and men (1.8% to 11.0%; PR=6.05 [3.19-14.31]). In 2024-26, 43.8% of those using pouches as a cessation aid were aged 18-24 and 69.5% were men. Pouch users also commonly reported using e-cigarettes (49.6%) or over-the-counter nicotine replacement therapy (37.9%) during the same quit attempt. Unadjusted quit success was 33.5% [27.1-39.9] among pouch users compared with 27.0% [25.9-28.1] among those who did not use pouches (OR=1.36 [1.02-1.82]). After adjustment, the association was attenuated (ORadj=1.15 [0.80-1.65]), with the 95%CI compatible with both a modest adverse association and a modest to large benefit. The association differed according to concurrent e-cigarette use (pinteraction=0.002): among those not using e-cigarettes as a cessation aid, pouch use was associated with higher quit success (ORadj=1.91 [1.23-2.97]), whereas evidence of an association among e-cigarette users was uncertain (ORadj=0.63 [0.36-1.11]). ConclusionsUse of nicotine pouches as a smoking cessation aid increased substantially in Great Britain between 2021 and 2026, particularly among younger adults and men. Pouches were frequently used alongside other cessation aids. While the overall association with quit success was uncertain, pouch use was associated with higher quit success among those not using e-cigarettes. If causal, this suggests a potential role for pouches among people not already using an established cessation aid.
ER -