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Peer-reviewedCC BYJournal of functional morphology and kinesiology

Structural Remodeling of the Lumbar Spine Following Non-Surgical Spinal Decompression: An Automated MRI Study.

  • Jacob A Connolly1,2,3
  • Nathan Molinier4,5
  • Kenneth A Weber6
  • Julien Cohen-Adad4,5
  • Nathan D Schilaty1,2,7
7 affiliations
  1. 1Neurosurgery, Brain & Spine, University of South Florida, 13220 USF Laurel Drive MDF 2108, Tampa, FL 33620, USA.
  2. 2Center for Neuromusculoskeletal Research, University of South Florida, Tampa, FL 33620, USA.
  3. 3Morsani College of Medicine, University of South Florida, Tampa, FL 33602, USA.
  4. 4Genie Electrique, Polytechnique Montreal (Ecole Polytechnique), 2900 Edouard-Montpetit Bld, Montreal, QC H3T 1J4, Canada.
  5. 5Mila-Quebec AI Institute, Montreal, QC H2S 3H1, Canada.
  6. 6Anesthesiology, Perioperative and Pain Medicine,Stanford University School of Medicine, 1070 Arastradero Road, Suite 200, Palo Alto, CA 94304, USA.
  7. 7Medical Engineering, University of South Florida, Tampa, FL 33620, USA.
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Abstract

Background and Objectives: To investigate MRI changes using SpineReport (r20260928) following non-surgical spinal decompression (NSSD) in patients with chronic low back pain (cLBP). We conducted a retrospective review of patients treated with NSSD who obtained MRI within 6 months of treatment initiation. Methods: Thirty-six subjects (20 F, 16 M), with a mean age of 55.9 ± 16.4 years, were treated at the USF Health Chiropractic Clinic, Department of Neurosurgery, Brain & Spine. NSSD using DRX9000® (Excite Medical, Tampa, FL, USA) was utilized, with a median of 20 (20, 25) treatments. Treatment levels included L3 (n = 2), L4 (n = 18), and L5 (n = 16). Sagittal T2-weighted images were processed using TotalSpineSeg (r20251124) for automated segmentation, with SpineReport used to quantify disc, vertebrae, spinal canal, and intervertebral foramen metrics. Results: Mean pain scores improved by 3.4 ± 1.8 from 5.6 ± 1.6 (p < 0.001), while Oswestry Disability Index scores improved by 10.8 ± 9.1 from 17.3 ± 8.0 (p < 0.001). At the treated level, spinal canal cross-sectional area increased from 170.9 to 175.8 mm² (2.9%, p = 0.040), and right-left diameter increased from 16.0 to 16.3 mm (1.9%, p = 0.025). Disc volume decreased from 7762.8 to 7449.5 mm³ (-4.0%, p = 0.046). No significant changes were observed in disc thickness, DHI, intervertebral foramen area, or vertebral measurements (p > 0.05). Conclusions: SpineReport enabled automated quantification of key spinal structures. NSSD was associated with increased spinal canal dimensions and improved symptoms. Further research is needed to determine the persistence and clinical significance of these structural changes.

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Cite

BibTeXRIS
BibTeX
@article{connolly2026structural,
  title = {{Structural Remodeling of the Lumbar Spine Following Non-Surgical Spinal Decompression: An Automated MRI Study.}},
  author = {Jacob A Connolly and Nathan Molinier and Kenneth A Weber and Julien Cohen-Adad and Nathan D Schilaty},
  journal = {Journal of functional morphology and kinesiology},
  year = {2026},
  month = sep,
  doi = {10.3390/jfmk11040390},
  url = {https://europepmc.org/article/MED/42924669},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Structural Remodeling of the Lumbar Spine Following Non-Surgical Spinal Decompression: An Automated MRI Study.
AU  - Jacob A Connolly
AU  - Nathan Molinier
AU  - Kenneth A Weber
AU  - Julien Cohen-Adad
AU  - Nathan D Schilaty
PY  - 2026
DA  - 2026/09/29
JO  - Journal of functional morphology and kinesiology
DO  - 10.3390/jfmk11040390
UR  - https://europepmc.org/article/MED/42924669
AB  - Background and Objectives: To investigate MRI changes using SpineReport (r20260928) following non-surgical spinal decompression (NSSD) in patients with chronic low back pain (cLBP). We conducted a retrospective review of patients treated with NSSD who obtained MRI within 6 months of treatment initiation. Methods: Thirty-six subjects (20 F, 16 M), with a mean age of 55.9 ± 16.4 years, were treated at the USF Health Chiropractic Clinic, Department of Neurosurgery, Brain & Spine. NSSD using DRX9000® (Excite Medical, Tampa, FL, USA) was utilized, with a median of 20 (20, 25) treatments. Treatment levels included L3 (n = 2), L4 (n = 18), and L5 (n = 16). Sagittal T2-weighted images were processed using TotalSpineSeg (r20251124) for automated segmentation, with SpineReport used to quantify disc, vertebrae, spinal canal, and intervertebral foramen metrics. Results: Mean pain scores improved by 3.4 ± 1.8 from 5.6 ± 1.6 (p < 0.001), while Oswestry Disability Index scores improved by 10.8 ± 9.1 from 17.3 ± 8.0 (p < 0.001). At the treated level, spinal canal cross-sectional area increased from 170.9 to 175.8 mm² (2.9%, p = 0.040), and right-left diameter increased from 16.0 to 16.3 mm (1.9%, p = 0.025). Disc volume decreased from 7762.8 to 7449.5 mm³ (-4.0%, p = 0.046). No significant changes were observed in disc thickness, DHI, intervertebral foramen area, or vertebral measurements (p > 0.05). Conclusions: SpineReport enabled automated quantification of key spinal structures. NSSD was associated with increased spinal canal dimensions and improved symptoms. Further research is needed to determine the persistence and clinical significance of these structural changes.
SN  - 2411-5142
ER  -