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Peer-reviewedCC BY-NC-NDJournal of pharmaceutical analysis

Panax quinquefolius derived extracellular vesicles promote post-chemotherapy immune reconstitution through the remodeling functions of macrophages via the NOD2/RIP2 axis.

  • Jixu Wu1
  • Yu Zhang1
  • Jinghong Xu1
  • Lin Dong1
  • Xiuhua Zhang2
  • Weijuan Huang1
  • Liyan Song1
  • Rongmin Yu1
  • Fei Liu2
  • Jianhua Zhu1
  1. 1Biotechnological Institute of Chinese Materia Medica, College of Pharmacy, Jinan University, Guangzhou, 511443, China.
  2. 2Shandong Provincial Key Laboratory of Carbohydrate and Glycoconjugate Drugs, Shandong Academy of Pharmaceutical Sciences, Jinan, 250101, China.
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Abstract

• PQEVs preparation was improved via enzymatic hydrolysis. • PQEVs were rich in immune-active components. • PQEVs acted via the NOD2/RIP2-MAPK/NF-κB pathway. • Plant cell culture enabled scalable PQEVs biomanufacturing.

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Cite

BibTeXRIS
BibTeX
@article{wu2026panax,
  title = {{Panax quinquefolius derived extracellular vesicles promote post-chemotherapy immune reconstitution through the remodeling functions of macrophages via the NOD2/RIP2 axis.}},
  author = {Jixu Wu and Yu Zhang and Jinghong Xu and Lin Dong and Xiuhua Zhang and Weijuan Huang and Liyan Song and Rongmin Yu and Fei Liu and Jianhua Zhu},
  journal = {Journal of pharmaceutical analysis},
  year = {2026},
  month = jun,
  doi = {10.1016/j.jpha.2026.101695},
  url = {https://europepmc.org/article/MED/42997589},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Panax quinquefolius derived extracellular vesicles promote post-chemotherapy immune reconstitution through the remodeling functions of macrophages via the NOD2/RIP2 axis.
AU  - Jixu Wu
AU  - Yu Zhang
AU  - Jinghong Xu
AU  - Lin Dong
AU  - Xiuhua Zhang
AU  - Weijuan Huang
AU  - Liyan Song
AU  - Rongmin Yu
AU  - Fei Liu
AU  - Jianhua Zhu
PY  - 2026
DA  - 2026/06/04
JO  - Journal of pharmaceutical analysis
DO  - 10.1016/j.jpha.2026.101695
UR  - https://europepmc.org/article/MED/42997589
AB  - • PQEVs preparation was improved via enzymatic hydrolysis. • PQEVs were rich in immune-active components. • PQEVs acted via the NOD2/RIP2-MAPK/NF-κB pathway. • Plant cell culture enabled scalable PQEVs biomanufacturing.
SN  - 2095-1779
SN  - 2214-0883
ER  -