The short-term impact of ambient air pollution on years of life lost from cancer in Pudong New Area, Shanghai: A time series study
- 1School of Public Health, Fudan University, Shanghai, China
- 2Shanghai Pudong New Area Centre for Disease Control and Prevention (Shanghai Pudong New Area Health Supervision Institute), Shanghai, China
Abstract
Objectives: Previous studies have shown that ambient air pollution was associated with an increased risk of cancer mortality. However, the mortality outcome treated every death equally and ignored the significance of premature death. Methods: We conducted a time series study to evaluate the short-term impact of ambient air pollution on years of life lost (YLLs) from cancer in Pudong New Area, Shanghai. Data on air pollutants, meteorological factors, cancer deaths, and years of life lost were collected from 2013 to 2021. In this study, the distributed lag nonlinear model (DLNM) combined with linear (for YLLs) and quasi-Poisson (for mortality) regression models was used to investigate the lag-specific association between air pollution exposure and two outcome indicators of cancer. A stratified analysis was performed according to sex, age, and education. Results: For YLLs, per 10 μg/m3 increase in PM2.5, PM10, SO2, NO2, and O3 exposure was significantly associated with YLL increases of 2.22 (95% CI: 0.71, 3.74), 1.04 (95% CI: 0.17, 1.91), 5.05 (95% CI: 0.74, 9.36), 1.88 (95% CI: 0.09, 3.66), and 0.96 (95% CI: 0.14, 1.78) years on lag0-1, respectively. Marginal differences in impact estimates were observed among men, younger populations, and those with higher education. In addition, the difference in the impact of O3 exposure on cancer mortality among low- and high-education subgroups was statistically significant. Conclusions: Short-term exposure to ambient air pollution was positively associated with increases in YLLs and cancer mortality in Pudong New Area, Shanghai.
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BibTeX
@article{zhong2026shortterm,
title = {{The short-term impact of ambient air pollution on years of life lost from cancer in Pudong New Area, Shanghai: A time series study}},
author = {Xing Zhong and Jiayi Sheng and Yichen Chen and Hua Chen and Siyue Han and Xiaobin Qu and Lianghong Sun and Sen Wang and Caixia Hu and Lipeng Hao},
journal = {PLOS One},
year = {2026},
month = oct,
doi = {10.1371/journal.pone.0360049},
url = {https://doi.org/10.1371/journal.pone.0360049},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - The short-term impact of ambient air pollution on years of life lost from cancer in Pudong New Area, Shanghai: A time series study
AU - Xing Zhong
AU - Jiayi Sheng
AU - Yichen Chen
AU - Hua Chen
AU - Siyue Han
AU - Xiaobin Qu
AU - Lianghong Sun
AU - Sen Wang
AU - Caixia Hu
AU - Lipeng Hao
PY - 2026
DA - 2026/10/27
JO - PLOS One
DO - 10.1371/journal.pone.0360049
UR - https://doi.org/10.1371/journal.pone.0360049
AB - Objectives: Previous studies have shown that ambient air pollution was associated with an increased risk of cancer mortality. However, the mortality outcome treated every death equally and ignored the significance of premature death. Methods: We conducted a time series study to evaluate the short-term impact of ambient air pollution on years of life lost (YLLs) from cancer in Pudong New Area, Shanghai. Data on air pollutants, meteorological factors, cancer deaths, and years of life lost were collected from 2013 to 2021. In this study, the distributed lag nonlinear model (DLNM) combined with linear (for YLLs) and quasi-Poisson (for mortality) regression models was used to investigate the lag-specific association between air pollution exposure and two outcome indicators of cancer. A stratified analysis was performed according to sex, age, and education. Results: For YLLs, per 10 μg/m3 increase in PM2.5, PM10, SO2, NO2, and O3 exposure was significantly associated with YLL increases of 2.22 (95% CI: 0.71, 3.74), 1.04 (95% CI: 0.17, 1.91), 5.05 (95% CI: 0.74, 9.36), 1.88 (95% CI: 0.09, 3.66), and 0.96 (95% CI: 0.14, 1.78) years on lag0-1, respectively. Marginal differences in impact estimates were observed among men, younger populations, and those with higher education. In addition, the difference in the impact of O3 exposure on cancer mortality among low- and high-education subgroups was statistically significant. Conclusions: Short-term exposure to ambient air pollution was positively associated with increases in YLLs and cancer mortality in Pudong New Area, Shanghai.
SN - 1932-6203
ER -