PreprintCC BYmedRxiv
Seroprevalence of viral hemorrhagic fevers and arboviral infections among febrile patients in Forest Guinea
- 1Bernhard Nocht Institute for Tropical Medicine (BNITM), Hamburg, Germany
Abstract
Between 2017 and 2024, routine diagnostics surveillance in Guinea detected several confirmed viral hemorrhagic fever (VHF) cases among febrile patients. To assess exposure to Lassa virus and other viral pathogens, we conducted a retrospective cross-sectional seroprevalence study in Forest Guinea (Gueckedou and NZerekore). Lassa virus seroprevalence was 56.0% in the Gueckedou study group and 29.8% in the NZerekore study group. Seropositivity increased with age in both study groups, suggesting cumulative exposure. Samples from Gueckedou laboratory were also tested for other pathogens, and antibodies against Marburg virus (5.8%), Zika virus (5.4%) and Crimean-Congo haemorrhagic fever virus (1.2%) were detected.
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BibTeX
@misc{koundouno2026seroprevalence,
title = {{Seroprevalence of viral hemorrhagic fevers and arboviral infections among febrile patients in Forest Guinea}},
author = {F. R. Koundouno and Y. Sidibe and H. Soubrier and K. Kourouma and S. Koulemou and T. E. Millimouno and F. M. Tolno and S. L. Millimono and K. Ifono and F. M. Kamano and M. D. Barry and B. Sonomy and M. Traore and K. Keita and M. Hinrichs and B. Becker Ziaja and E. V. Nelson and C. Jacobsen and A. Thielebein and L. Oestereich and M. Pahlmann and B. Escudero-Perez and R. Krumkamp and S. Guenther and M. Kolie and K. Keita and S. H. Guilavogui and N. Magassouba and S. Boumbaly and G. Annibaldis and S. Duraffour},
howpublished = {medRxiv},
year = {2026},
month = sep,
doi = {10.64898/2026.09.02.26362016},
url = {https://www.medrxiv.org/content/10.64898/2026.09.02.26362016v1},
note = {CC BY},
}
RIS
TY - UNPB
TI - Seroprevalence of viral hemorrhagic fevers and arboviral infections among febrile patients in Forest Guinea
AU - F. R. Koundouno
AU - Y. Sidibe
AU - H. Soubrier
AU - K. Kourouma
AU - S. Koulemou
AU - T. E. Millimouno
AU - F. M. Tolno
AU - S. L. Millimono
AU - K. Ifono
AU - F. M. Kamano
AU - M. D. Barry
AU - B. Sonomy
AU - M. Traore
AU - K. Keita
AU - M. Hinrichs
AU - B. Becker Ziaja
AU - E. V. Nelson
AU - C. Jacobsen
AU - A. Thielebein
AU - L. Oestereich
AU - M. Pahlmann
AU - B. Escudero-Perez
AU - R. Krumkamp
AU - S. Guenther
AU - M. Kolie
AU - K. Keita
AU - S. H. Guilavogui
AU - N. Magassouba
AU - S. Boumbaly
AU - G. Annibaldis
AU - S. Duraffour
PY - 2026
DA - 2026/09/02
PB - medRxiv
DO - 10.64898/2026.09.02.26362016
UR - https://www.medrxiv.org/content/10.64898/2026.09.02.26362016v1
AB - Between 2017 and 2024, routine diagnostics surveillance in Guinea detected several confirmed viral hemorrhagic fever (VHF) cases among febrile patients. To assess exposure to Lassa virus and other viral pathogens, we conducted a retrospective cross-sectional seroprevalence study in Forest Guinea (Gueckedou and NZerekore). Lassa virus seroprevalence was 56.0% in the Gueckedou study group and 29.8% in the NZerekore study group. Seropositivity increased with age in both study groups, suggesting cumulative exposure. Samples from Gueckedou laboratory were also tested for other pathogens, and antibodies against Marburg virus (5.8%), Zika virus (5.4%) and Crimean-Congo haemorrhagic fever virus (1.2%) were detected.
ER -