Analysis of influencing factors of acute kidney injury secondary to acute heart failure
- 1Department of Cardiology,The 909th Hospital,Dongnan Hospital of Xiamen University,Zhangzhou,Fujian 363000,China
Abstract
Objective To explore the influencing factors of nosocomial secondary acute kidney injury(AKI)in patients with acute heart failure(AHF),aiming to provide clinical evidence for early identification and intervention of AKI.Methods The clinical data of 216 patients diagnosed with AHF and admitted to Dongnan Hospital of Xiamen University from January 2021 to January 2023 were retrospectively analyzed. All patients were divided into the AKI group(n=46)and the non-AKI group(n=170)according to the presence or absence of AKI during hospitalization. The general data and clinical data of the two groups were compared,and multivariate logistic regression analysis was performed to screen the independent influencing factors for secondary AKI in AHF patients. Results The proportions of hypertension,diabetes,NYHA grade Ⅳ,and contrast medium application,as well as the level of N-terminal pro-brain natriuretic peptide(NT-proBNP)were significantly higher in the AKI group compared to the non-AKI group(P<0.05). Multivariate logistic regression analysis demonstrated that diabetes mellitus (OR=5.096,95% CI:1.732-14.977),NT-proBNP level(OR=0.996,95%CI:0.994-0.997),and contrast medium use(OR=3.884,95%CI:1.313-11.487)were independent influencing factors for secondary AKI in AHF patients(P<0.05). Conclusion Diabetes mellitus,NT-proBNP level and contrast medium exposure are all associated with the risk of secondary AKI in patients with AHF. Close monitoring and early intervention should be implemented for high-risk AHF patients to prevent the occurrence of AKI.
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BibTeX
@article{yiping2026analysis,
title = {{Analysis of influencing factors of acute kidney injury secondary to acute heart failure}},
author = {XU Yiping and PENG Qing and LIN Genghai},
journal = {Zhongguo linchuang yanjiu},
year = {2026},
month = oct,
doi = {10.13429/j.cnki.cjcr.2026.10.023},
url = {https://doi.org/10.13429/j.cnki.cjcr.2026.10.023},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Analysis of influencing factors of acute kidney injury secondary to acute heart failure
AU - XU Yiping
AU - PENG Qing
AU - LIN Genghai
PY - 2026
DA - 2026/10/26
JO - Zhongguo linchuang yanjiu
DO - 10.13429/j.cnki.cjcr.2026.10.023
UR - https://doi.org/10.13429/j.cnki.cjcr.2026.10.023
AB - Objective To explore the influencing factors of nosocomial secondary acute kidney injury(AKI)in patients with acute heart failure(AHF),aiming to provide clinical evidence for early identification and intervention of AKI.Methods The clinical data of 216 patients diagnosed with AHF and admitted to Dongnan Hospital of Xiamen University from January 2021 to January 2023 were retrospectively analyzed. All patients were divided into the AKI group(n=46)and the non-AKI group(n=170)according to the presence or absence of AKI during hospitalization. The general data and clinical data of the two groups were compared,and multivariate logistic regression analysis was performed to screen the independent influencing factors for secondary AKI in AHF patients. Results The proportions of hypertension,diabetes,NYHA grade Ⅳ,and contrast medium application,as well as the level of N-terminal pro-brain natriuretic peptide(NT-proBNP)were significantly higher in the AKI group compared to the non-AKI group(P<0.05). Multivariate logistic regression analysis demonstrated that diabetes mellitus (OR=5.096,95% CI:1.732-14.977),NT-proBNP level(OR=0.996,95%CI:0.994-0.997),and contrast medium use(OR=3.884,95%CI:1.313-11.487)were independent influencing factors for secondary AKI in AHF patients(P<0.05). Conclusion Diabetes mellitus,NT-proBNP level and contrast medium exposure are all associated with the risk of secondary AKI in patients with AHF. Close monitoring and early intervention should be implemented for high-risk AHF patients to prevent the occurrence of AKI.
SN - 1674-8182
ER -