Skip to content
DraconiticResearch
Search Sources API
197,768 studies31 sourcesUpdated 53 min ago
Peer-reviewedCC BYClinical Epidemiology and Global Health

Association between parental cardiometabolic risk and longitudinal weight velocity in rural Indian children

  • Mugdha Deshpande1
  • Nikhil Shah2
  • Vaman Khadilkar1
  • Anuradha Khadilkar3
  1. 1Department of Growth and Pediatric Endocrinology, Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharashtra, India
  2. 2Department of Growth and Pediatric Endocrinology, Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharashtra, India; Department of Pediatric Endocrinology, Surya Hospital, Mumbai, Maharashtra, India
  3. 3Department of Growth and Pediatric Endocrinology, Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharashtra, India; Corresponding author. Hirabai Cowasji Jehangir Medical Research Institute, Block V Lower Basement Jehangir Hospital, 32 Sassoon Road, Pune, 411001, India.
Read full textPDFDOICite

Abstract

Background: Childhood weight velocity may help identify altered growth patterns and future cardiometabolic risk, while parental cardiometabolic health may influence childhood weight gain, particularly in rapidly transitioning rural populations. Therefore, our objectives were to characterize longitudinal weight velocity patterns in rural children and examine their association with parental cardiometabolic risk. Methods: Data were analysed from YUVAAN-multigenerational cohort comprising 1323 parent-child triads from rural India. Children were followed annually for up to three years. Weight velocity was calculated using age-and sex-specific percentiles; values ≥ 75th percentile was considered elevated. Parental cardiometabolic risk was assessed using composite score based on AHA/NHLBI criteria. Longitudinal associations between parental cardiometabolic risk and childhood weight velocity were examined using generalized estimating equations. Results: Elevated weight velocity was found in 28.1% children. Children with parental cardiometabolic risk demonstrated higher weight velocity than those without risk(4.0 ± 2.3 vs. 3.5 ± 2.2 kg, p < 0.001). A graded association was observed between parental cardiometabolic risk and elevated weight velocity, with strongest association among children in whom both parents had cardiometabolic risk(OR: 2.66, 95% CI: 1.90-3.71,p: 0.0001). Elevated parental waist circumference, hypertension, and maternal hyperglycaemia showed strongest associations. Sex-stratified analyses demonstrated stronger associations in girls, whereas in boys, higher weight velocity was observed only when both parents had cardiometabolic risk. Conclusion: Parental cardiometabolic risk was associated with greater weight velocity in rural Indian children, particularly when both parents were affected, with differences by child sex. These findings suggest intergenerational clustering of cardiometabolic vulnerability and may help identify children at risk of accelerated weight gain for earlier family-based prevention.

Related

  1. Parental Feeding Practices, Child Eating Behaviours, and Their Association with Metabolic Control in Children with Type 1 Diabetes: A Systematic Review
    Raquel Oliveira, José Miguel Martinez-Sanz, João P. M. Lima +2
    Pediatric reportsPeer-reviewedCC BYFull textGeneral medicineEurope PMC
  2. Association between normal-weight central obesity and cardiometabolic disorders: a longitudinal analysis from health check-up data.
    Yang Cheng, Hui Zheng, Hongli Yin +3
    BMC cardiovascular disordersPeer-reviewedCC BY-NC-NDFull textEndocrinology & metabolismEurope PMCDOAJ
  3. Parental perception of child weight status and its association to overweight and obesity in children
    TA Rodrigues, SP Cunha, HA Alencastre +1
    The European Journal of Public HealthPeer-reviewedCC BY-NC 4.0Full textEpidemiology & public healthPMCEurope PMC
  4. Parental obesity and offspring cardiometabolic trajectories from childhood to adulthood
    Yi Qian, Chao-Nan Gao, Nai-Jun Wan +1
    Frontiers in public healthPeer-reviewedCC BYFull textEpidemiology & public healthEurope PMC
  5. Children’s Perception of Parental Body Size and Its Association with Their Desire to Be Like the Parent
    Abdullah Kaan Kurt, Serdar Karakullukçu
    Children (Basel, Switzerland)Peer-reviewedCC BYFull textEpidemiology & public healthEurope PMCDOAJ

Cite

BibTeXRIS
BibTeX
@article{deshpande2026association,
  title = {{Association between parental cardiometabolic risk and longitudinal weight velocity in rural Indian children}},
  author = {Mugdha Deshpande and Nikhil Shah and Vaman Khadilkar and Anuradha Khadilkar},
  journal = {Clinical Epidemiology and Global Health},
  year = {2026},
  month = oct,
  doi = {10.1016/j.cegh.2026.102511},
  url = {https://doi.org/10.1016/j.cegh.2026.102511},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Association between parental cardiometabolic risk and longitudinal weight velocity in rural Indian children
AU  - Mugdha Deshpande
AU  - Nikhil Shah
AU  - Vaman Khadilkar
AU  - Anuradha Khadilkar
PY  - 2026
DA  - 2026/10/30
JO  - Clinical Epidemiology and Global Health
DO  - 10.1016/j.cegh.2026.102511
UR  - https://doi.org/10.1016/j.cegh.2026.102511
AB  - Background: Childhood weight velocity may help identify altered growth patterns and future cardiometabolic risk, while parental cardiometabolic health may influence childhood weight gain, particularly in rapidly transitioning rural populations. Therefore, our objectives were to characterize longitudinal weight velocity patterns in rural children and examine their association with parental cardiometabolic risk. Methods: Data were analysed from YUVAAN-multigenerational cohort comprising 1323 parent-child triads from rural India. Children were followed annually for up to three years. Weight velocity was calculated using age-and sex-specific percentiles; values ≥ 75th percentile was considered elevated. Parental cardiometabolic risk was assessed using composite score based on AHA/NHLBI criteria. Longitudinal associations between parental cardiometabolic risk and childhood weight velocity were examined using generalized estimating equations. Results: Elevated weight velocity was found in 28.1% children. Children with parental cardiometabolic risk demonstrated higher weight velocity than those without risk(4.0 ± 2.3 vs. 3.5 ± 2.2 kg, p < 0.001). A graded association was observed between parental cardiometabolic risk and elevated weight velocity, with strongest association among children in whom both parents had cardiometabolic risk(OR: 2.66, 95% CI: 1.90-3.71,p: 0.0001). Elevated parental waist circumference, hypertension, and maternal hyperglycaemia showed strongest associations. Sex-stratified analyses demonstrated stronger associations in girls, whereas in boys, higher weight velocity was observed only when both parents had cardiometabolic risk. Conclusion: Parental cardiometabolic risk was associated with greater weight velocity in rural Indian children, particularly when both parents were affected, with differences by child sex. These findings suggest intergenerational clustering of cardiometabolic vulnerability and may help identify children at risk of accelerated weight gain for earlier family-based prevention.
SN  - 2213-3984
SN  - 2452-0918
ER  -