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PreprintAll rights reservedbioRxiv

Cell-state-dependent responses to PLK1 inhibition reveal a non-canonical microtubule-endolysosomal vulnerability in quiescent leukemia stem cells

  • Q. Liu
  • M. Gojsevic
  • A. Varesi
  • A. Subedi
  • C. Xu
  • F. A. Yeung
  • B. Dinel
  • N. Mbong
  • L. Jin
  • A. Mitchell
  • C. Lim
  • P. J. Janssen
9 more authors
  • H. Boutzen
  • A. Arruda
  • M. D. Minden
  • E. R. Lechman
  • B. Raught
  • S. N. Chan
  • G. D. Bader
  • K. B. Kaufmann1
  • J. C. Wang
  1. 1Princess Margaret Cancer Centre, University Health Network, Toronto, Canada
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Cite

BibTeXRIS
BibTeX
@misc{liu2026cellstatedependent,
  title = {{Cell-state-dependent responses to PLK1 inhibition reveal a non-canonical microtubule-endolysosomal vulnerability in quiescent leukemia stem cells}},
  author = {Q. Liu and M. Gojsevic and A. Varesi and A. Subedi and C. Xu and F. A. Yeung and B. Dinel and N. Mbong and L. Jin and A. Mitchell and C. Lim and P. J. Janssen and H. Boutzen and A. Arruda and M. D. Minden and E. R. Lechman and B. Raught and S. N. Chan and G. D. Bader and K. B. Kaufmann and J. C. Wang},
  howpublished = {bioRxiv},
  year = {2026},
  month = aug,
  doi = {10.64898/2026.08.25.746864},
  url = {https://www.biorxiv.org/content/10.64898/2026.08.25.746864v2},
}
RIS
TY  - UNPB
TI  - Cell-state-dependent responses to PLK1 inhibition reveal a non-canonical microtubule-endolysosomal vulnerability in quiescent leukemia stem cells
AU  - Q. Liu
AU  - M. Gojsevic
AU  - A. Varesi
AU  - A. Subedi
AU  - C. Xu
AU  - F. A. Yeung
AU  - B. Dinel
AU  - N. Mbong
AU  - L. Jin
AU  - A. Mitchell
AU  - C. Lim
AU  - P. J. Janssen
AU  - H. Boutzen
AU  - A. Arruda
AU  - M. D. Minden
AU  - E. R. Lechman
AU  - B. Raught
AU  - S. N. Chan
AU  - G. D. Bader
AU  - K. B. Kaufmann
AU  - J. C. Wang
PY  - 2026
DA  - 2026/08/25
PB  - bioRxiv
DO  - 10.64898/2026.08.25.746864
UR  - https://www.biorxiv.org/content/10.64898/2026.08.25.746864v2
ER  -