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Peer-reviewedCC BYDiagnostics (Basel, Switzerland)

Diagnostic Communication and the Care That Follows: A Critical Narrative Review.

  1. 1School of Health and Care Sciences, University of West Attica, 12243 Athens, Greece.

Abstract

An accurate diagnosis does not ensure that a patient understands its implications or receives appropriate care. This critical narrative review draws on purposively selected literature studies on diagnostic labels, explanations of test results, nocebo effects and care after diagnostic revision. Terminology experiments show changes in perceived severity and stated preferences, often in hypothetical settings. Clinical effects on symptoms and healthcare use depend on the intervention, comparator and outcome; explanation is frequently combined with treatment changes. Nocebo experiments demonstrate possible symptom mechanisms, not the cause of an individual patient's continuing symptoms. Studies of diagnostic follow-up identify a separate problem: accurate or revised findings may fail to inform subsequent care. The synthesis distinguishes evidence for changing understanding, relieving symptoms and completing appropriate clinical action. A documented misunderstanding or obsolete instruction can warrant correction while symptom assessment continues. Evaluation should measure accurate understanding, informed choices and care received, with symptoms assessed separately. Truthful disclosure and follow-up remain responsibilities even when symptom benefit is uncertain.

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BibTeX
@article{xanthos2026diagnostic,
  title = {{Diagnostic Communication and the Care That Follows: A Critical Narrative Review.}},
  author = {Theodoros Xanthos},
  journal = {Diagnostics (Basel, Switzerland)},
  year = {2026},
  month = oct,
  doi = {10.3390/diagnostics16193211},
  url = {https://europepmc.org/article/MED/42882366},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Diagnostic Communication and the Care That Follows: A Critical Narrative Review.
AU  - Theodoros Xanthos
PY  - 2026
DA  - 2026/10/03
JO  - Diagnostics (Basel, Switzerland)
DO  - 10.3390/diagnostics16193211
UR  - https://europepmc.org/article/MED/42882366
AB  - An accurate diagnosis does not ensure that a patient understands its implications or receives appropriate care. This critical narrative review draws on purposively selected literature studies on diagnostic labels, explanations of test results, nocebo effects and care after diagnostic revision. Terminology experiments show changes in perceived severity and stated preferences, often in hypothetical settings. Clinical effects on symptoms and healthcare use depend on the intervention, comparator and outcome; explanation is frequently combined with treatment changes. Nocebo experiments demonstrate possible symptom mechanisms, not the cause of an individual patient's continuing symptoms. Studies of diagnostic follow-up identify a separate problem: accurate or revised findings may fail to inform subsequent care. The synthesis distinguishes evidence for changing understanding, relieving symptoms and completing appropriate clinical action. A documented misunderstanding or obsolete instruction can warrant correction while symptom assessment continues. Evaluation should measure accurate understanding, informed choices and care received, with symptoms assessed separately. Truthful disclosure and follow-up remain responsibilities even when symptom benefit is uncertain.
SN  - 2075-4418
ER  -