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Peer-reviewedCC BYStem Cell Research

Generation of four human induced pluripotent stem cell lines derived from patients with corticosteroid-associated central serous chorioretinopathy

Abstract

Peripheral blood from four male patients with corticosteroid-related central serous chorioretinopathy (CSC) was used to generate human induced pluripotent stem cells (hiPSCs). Non-integrating episomal vectors were employed to deliver the reprogramming factors. All hiPSCs displayed typical morphology, expressed markers of the undifferentiated state, demonstrated the ability to differentiate into the three-germ layers, and exhibited normal karyotypes. These hiPSC lines offer a valuable model to study CSC pathogenesis.

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BibTeX
@article{galuh2026generation,
  title = {{Generation of four human induced pluripotent stem cell lines derived from patients with corticosteroid-associated central serous chorioretinopathy}},
  author = {Sekar Galuh and Karine Raymond and Joost Brinks and Elon H.C. van Dijk and Christian Freund and Onno Meijer and Camiel J.F. Boon},
  journal = {Stem Cell Research},
  year = {2026},
  month = aug,
  doi = {10.1016/j.scr.2026.104006},
  url = {https://hal.science/hal-05732027v1},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Generation of four human induced pluripotent stem cell lines derived from patients with corticosteroid-associated central serous chorioretinopathy
AU  - Sekar Galuh
AU  - Karine Raymond
AU  - Joost Brinks
AU  - Elon H.C. van Dijk
AU  - Christian Freund
AU  - Onno Meijer
AU  - Camiel J.F. Boon
PY  - 2026
DA  - 2026/08/31
JO  - Stem Cell Research
DO  - 10.1016/j.scr.2026.104006
UR  - https://hal.science/hal-05732027v1
AB  - Peripheral blood from four male patients with corticosteroid-related central serous chorioretinopathy (CSC) was used to generate human induced pluripotent stem cells (hiPSCs). Non-integrating episomal vectors were employed to deliver the reprogramming factors. All hiPSCs displayed typical morphology, expressed markers of the undifferentiated state, demonstrated the ability to differentiate into the three-germ layers, and exhibited normal karyotypes. These hiPSC lines offer a valuable model to study CSC pathogenesis.
SN  - 1876-7753
ER  -