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Peer-reviewedCC BY-NCOrganic & Biomolecular Chemistry

A case study of the MAC (masked acyl cyanide) oxyhomologation of N , N -dibenzyl- l -phenylalaninal with anti diastereoselectivity: preparation of (2 S ,3 S )-allophenylnorstatin esters

  • Xuefeng He
  • Marie Buchotte
  • Régis Guillot
  • Sandrine Deloisy
  • David Aitken
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Abstract

The three-component reaction proceeds with unhindered alcohols in good yield and high anti diastereoselectivity to give protected ester derivatives of (2 S ,3 S )-allophenylnorstatin and provides an expedient access to the amino acid itself.

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Cite

BibTeXRIS
BibTeX
@article{he2026case,
  title = {{A case study of the MAC (masked acyl cyanide) oxyhomologation of N , N -dibenzyl- l -phenylalaninal with anti diastereoselectivity: preparation of (2 S ,3 S )-allophenylnorstatin esters}},
  author = {Xuefeng He and Marie Buchotte and Régis Guillot and Sandrine Deloisy and David Aitken},
  journal = {Organic \& Biomolecular Chemistry},
  year = {2026},
  month = sep,
  doi = {10.1039/d1ob02411f},
  url = {https://hal.science/hal-05771350v1},
  note = {CC BY-NC},
}
RIS
TY  - JOUR
TI  - A case study of the MAC (masked acyl cyanide) oxyhomologation of N , N -dibenzyl- l -phenylalaninal with anti diastereoselectivity: preparation of (2 S ,3 S )-allophenylnorstatin esters
AU  - Xuefeng He
AU  - Marie Buchotte
AU  - Régis Guillot
AU  - Sandrine Deloisy
AU  - David Aitken
PY  - 2026
DA  - 2026/09/30
JO  - Organic & Biomolecular Chemistry
DO  - 10.1039/d1ob02411f
UR  - https://hal.science/hal-05771350v1
AB  - The three-component reaction proceeds with unhindered alcohols in good yield and high anti diastereoselectivity to give protected ester derivatives of (2 S ,3 S )-allophenylnorstatin and provides an expedient access to the amino acid itself.
SN  - 1477-0520
SN  - 1477-0539
ER  -