Total Thoracic Aortic "Pericardialization" for Multilevel Prosthetic Graft Infection.
- 1Department of Thoracic & Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio, USA. Electronic address: [email protected].
- 2Department of Thoracic & Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio, USA.
Abstract
Background
Prosthetic aortic infection involving composite roots and frozen elephant trunk components presents an extraordinary challenge with high mortality. We present a complex aortic reconstruction using custom bovine pericardial conduits.Case summary
A 55-year-old man with a history of a redo Bentall procedure and frozen elephant trunk implantation presented with extensive pan-aortic prosthetic infection, systemic septic emboli, and acute intracranial hemorrhage. Surgery focused on radical debridement and complete extrication of all synthetic material. The aortic root, ascending aorta, arch, and supra-aortic branches were entirely reconstructed using 4 intraoperatively hand-fashioned bovine pericardial tube grafts, creating a classic elephant trunk assembly. The patient was extubated on the day of surgery, discharged on day 7 without neurologic deficits, and remained infection-free at 3 months.Discussion
Radical excision and total aortic reconstruction using hand-made bovine pericardial grafts provide a completely biological, infection-resistant alternative for treating these highly complex conditions.
Related
- Skirted Prosthetic Valves Are Associated With Increased Risk of Subclinical Leaflet Thrombosis Following Transcatheter Aortic Valve Replacement: A Multicenter Study
- A snare-assisted pull-up technique for side-branch component delivery during thoracic endovascular aortic repair for distal aortic arch aneurysm using Gore Thoracic Branch Endoprosthesis
- Case Report: Prosthetic valve migration unmasking behçet disease after transcatheter aortic valve replacement
- Hybrid approach with thoracic endovascular treatment and abdominal aortic replacement for acute type B aortic dissection complicated by ruptured abdominal aortic aneurysm
- Integrated Analysis of Serotonin-Related Biomarkers in Thoracic Aortic Aneurysm Based on Machine Learning and Single-Cell Sequencing Data
BibTeX
@article{pasic2026total,
title = {{Total Thoracic Aortic "Pericardialization" for Multilevel Prosthetic Graft Infection.}},
author = {Miralem Pasic and Sanjay Chaubey and Kang An},
journal = {JACC. Case reports},
year = {2026},
month = oct,
doi = {10.1016/j.jaccas.2026.110322},
url = {https://europepmc.org/article/MED/42847578},
note = {CC BY},
}
RIS
TY - JOUR
TI - Total Thoracic Aortic "Pericardialization" for Multilevel Prosthetic Graft Infection.
AU - Miralem Pasic
AU - Sanjay Chaubey
AU - Kang An
PY - 2026
DA - 2026/10/01
JO - JACC. Case reports
DO - 10.1016/j.jaccas.2026.110322
UR - https://europepmc.org/article/MED/42847578
AB - Background Prosthetic aortic infection involving composite roots and frozen elephant trunk components presents an extraordinary challenge with high mortality. We present a complex aortic reconstruction using custom bovine pericardial conduits.Case summary A 55-year-old man with a history of a redo Bentall procedure and frozen elephant trunk implantation presented with extensive pan-aortic prosthetic infection, systemic septic emboli, and acute intracranial hemorrhage. Surgery focused on radical debridement and complete extrication of all synthetic material. The aortic root, ascending aorta, arch, and supra-aortic branches were entirely reconstructed using 4 intraoperatively hand-fashioned bovine pericardial tube grafts, creating a classic elephant trunk assembly. The patient was extubated on the day of surgery, discharged on day 7 without neurologic deficits, and remained infection-free at 3 months.Discussion Radical excision and total aortic reconstruction using hand-made bovine pericardial grafts provide a completely biological, infection-resistant alternative for treating these highly complex conditions.
SN - 2666-0849
ER -