Skip to content
DraconiticResearch
Search Sources API
194,226 studies31 sourcesUpdated 32 min ago
Peer-reviewedLicence not statedCancer research

Aberrant Accumulation of Cyclin D1 Rewires Glutamine Metabolism and Generates a Metabolic Vulnerability in Squamous Cell Carcinoma

  • Shuyuan Zhang1
  • Polly J. Phillips-Mason1
  • Bartosz Mucha1
  • Marganit Farago1
  • Guofang Zhang2
  • Cecilia Martin3,4
  • Andres J. Klein-Szanto5
  • Hiroshi Nakagawa3,4
  • Anil K. Rustgi3,4
  • Kwok-Kin Wong6
  • Brian S. Henick4,7
  • J. Alan Diehl1
7 affiliations
  1. 1Department of Biochemistry, Center for RNA Science and Therapeutics, Case Comprehensive Cancer Center; Case Western Reserve University, Cleveland, OH, USA.
  2. 2Division of Endocrinology, Metabolism, and Nutrition, Department of Medicine, Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
  3. 3Division of Digestive and Liver Diseases, Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, USA.
  4. 4Herbert Irving Comprehensive Cancer Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, USA.
  5. 5Histopathology Facility, Fox Chase Cancer Center, Philadelphia, PA, USA.
  6. 6Division of Hematology and Medical Oncology, Perlmutter Cancer Center, New York University, New York, NY, USA.
  7. 7Division of Hematology-Oncology, Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, USA.
Read full textDOICite

Related

  1. Glutamine Metabolism in Cardiac Hypertrophy
    Zhi-Guo Hu, Yao Yao, Yan Gong +1
    Reviews in cardiovascular medicinePeer-reviewedCC BYFull textCardiovascular medicineEurope PMC
  2. THERAPY RESISTANCE IN MELANOMA DRIVES CILIOGENESIS AND GLUTAMINE/ASPARTATE METABOLISM DEPENDENCY
    P. Lugato, R. Castro, C. Thomas +4
    bioRxivPreprintAll rights reservedFull textOncologybioRxiv
  3. Targeting SLC1A5-mediated glutamine metabolism overcomes PARP inhibitor resistance in ovarian cancer.
    Fang Han, Hongjie Du, Kunlin Tian +4
    Cell death & diseasePeer-reviewedCC BYFull textOncologyEurope PMCDOAJ
  4. ARHGAP40 suppresses clear cell renal cell carcinoma progression and is associated with altered glutamine-related metabolism and redox balance.
    Na You, Xiaoxia Wang, Caizhu Wang +7
    Cancer biology & therapyPeer-reviewedCC BYFull textGeneral medicineEurope PMC
  5. Glutamine and GLS1 are key metabolic checkpoints that Limit T cell Infiltration and Function in HNSCC
    S. M. Decking-Paede, I. Ugele, K. Dettmer +38
    bioRxivPreprintAll rights reservedFull textOncologybioRxiv

Cite

BibTeXRIS
BibTeX
@article{zhang2026aberrant,
  title = {{Aberrant Accumulation of Cyclin D1 Rewires Glutamine Metabolism and Generates a Metabolic Vulnerability in Squamous Cell Carcinoma}},
  author = {Shuyuan Zhang and Polly J. Phillips-Mason and Bartosz Mucha and Marganit Farago and Guofang Zhang and Cecilia Martin and Andres J. Klein-Szanto and Hiroshi Nakagawa and Anil K. Rustgi and Kwok-Kin Wong and Brian S. Henick and J. Alan Diehl},
  journal = {Cancer research},
  year = {2026},
  month = oct,
  doi = {10.1158/0008-5472.can-26-0389},
  url = {https://doi.org/10.1158/0008-5472.can-26-0389},
}
RIS
TY  - JOUR
TI  - Aberrant Accumulation of Cyclin D1 Rewires Glutamine Metabolism and Generates a Metabolic Vulnerability in Squamous Cell Carcinoma
AU  - Shuyuan Zhang
AU  - Polly J. Phillips-Mason
AU  - Bartosz Mucha
AU  - Marganit Farago
AU  - Guofang Zhang
AU  - Cecilia Martin
AU  - Andres J. Klein-Szanto
AU  - Hiroshi Nakagawa
AU  - Anil K. Rustgi
AU  - Kwok-Kin Wong
AU  - Brian S. Henick
AU  - J. Alan Diehl
PY  - 2026
DA  - 2026/10/05
JO  - Cancer research
DO  - 10.1158/0008-5472.can-26-0389
UR  - https://doi.org/10.1158/0008-5472.can-26-0389
SN  - 0008-5472
SN  - 1538-7445
ER  -