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Peer-reviewedCC BYJournal for ImmunoTherapy of Cancer

601 GARP–TGF-β1 blockade with livmoniplimab reprograms spatial tumor niches and enhances PD-1 inhibition in human tumor explants

  • Patrick Caplazi1
  • Tolga Turan2
  • Iraz Aydin3
  • Myles Dillon4
  • Shih-Hsun Chen5
  • Nadine Jahchan6
  • Tamar Uziel7
  • Durga Bhavani Dandamudi8
  • Mimi Refici8
  • Rhyannon H Spangler9
  • Michelle Belmont8
  • David Sharon9
5 more authors
  • Yoshiko Hashikawa9
  • Steven Chirieleison9
  • Kevin Kolahi9
  • Erik Huntzicker9
  • Pearlie K Burnette8
9 affiliations
  1. 11Genentech Research and Early Development, South San Francisco, California, USA
  2. 2Aff1 0000 0004 0572 4227grid.431072.3Immune-Oncology DiscoveryAbbVie Redwood City CA USA
  3. 3Atreca, Inc, South San Francisco, CA, USA
  4. 41Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA
  5. 5Cancer Immunology Discovery, Pfizer Inc, San Diego, California, USA
  6. 63Adicet Bio, Redwood City, CA, USA
  7. 72AbbVie Inc., North Chicago, IL, USA
  8. 8AbbVie, North Chicago, IL, USA
  9. 9AbbVie, San Francisco, CA, USA
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Cite

BibTeXRIS
BibTeX
@article{caplazi2026garptgfβ1,
  title = {{601 GARP–TGF-β1 blockade with livmoniplimab reprograms spatial tumor niches and enhances PD-1 inhibition in human tumor explants}},
  author = {Patrick Caplazi and Tolga Turan and Iraz Aydin and Myles Dillon and Shih-Hsun Chen and Nadine Jahchan and Tamar Uziel and Durga Bhavani Dandamudi and Mimi Refici and Rhyannon H Spangler and Michelle Belmont and David Sharon and Yoshiko Hashikawa and Steven Chirieleison and Kevin Kolahi and Erik Huntzicker and Pearlie K Burnette},
  journal = {Journal for ImmunoTherapy of Cancer},
  year = {2026},
  month = nov,
  doi = {10.1136/jitc-2026-sitc2026.0601},
  url = {https://doi.org/10.1136/jitc-2026-sitc2026.0601},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - 601 GARP–TGF-β1 blockade with livmoniplimab reprograms spatial tumor niches and enhances PD-1 inhibition in human tumor explants
AU  - Patrick Caplazi
AU  - Tolga Turan
AU  - Iraz Aydin
AU  - Myles Dillon
AU  - Shih-Hsun Chen
AU  - Nadine Jahchan
AU  - Tamar Uziel
AU  - Durga Bhavani Dandamudi
AU  - Mimi Refici
AU  - Rhyannon H Spangler
AU  - Michelle Belmont
AU  - David Sharon
AU  - Yoshiko Hashikawa
AU  - Steven Chirieleison
AU  - Kevin Kolahi
AU  - Erik Huntzicker
AU  - Pearlie K Burnette
PY  - 2026
DA  - 2026/11/08
JO  - Journal for ImmunoTherapy of Cancer
DO  - 10.1136/jitc-2026-sitc2026.0601
UR  - https://doi.org/10.1136/jitc-2026-sitc2026.0601
SN  - 2051-1426
ER  -