Skip to content
DraconiticResearch
Search Sources API
203,203 studies31 sourcesUpdated 44 min ago
Peer-reviewedCC BY-NCScience Advances

The Fireside Database: Large-scale evidence from 25,419 psychedelic support interactions

7 affiliations
  1. 1Fireside Project, Venice, CA, USA.
  2. 2Institute for Advanced Consciousness Studies, Santa Monica, CA, USA.
  3. 3Sorbonne Université CNRS, ERL U1338 Inserm, Paris, France.
  4. 4Learning Transitions, Learning Planet Institute and CY Cergy Paris University, Paris, France.
  5. 5Division of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, Thônex, Switzerland.
  6. 6Faculty of Medicine, University of Geneva, Geneva, Switzerland.
  7. 7Vision Point Systems Inc., Arlington, VA, USA.

Abstract

Most psychedelic experiences occur outside clinical settings, yet as policy frameworks rapidly expand to accommodate nonclinical use, no systematic data exist on who seeks psychedelic support, under what circumstances, or what makes that support effective. We present the Fireside Database, a US-based dataset comprising 25,419 peer support interactions conducted by 220 trained volunteers at Fireside Project's Psychedelic Support Line between April 2021 and February 2026. The released resource integrates structured interaction logs with volunteer-coded metadata and 2777 caller satisfaction surveys across five outcome dimensions. Psilocybin was the most commonly reported substance (59.9% of coded interactions), while cannabis produced the highest distress rate (47.2%). The nested data structure-with 50 supporters each completing ≥10 surveyed interactions-supports multilevel modeling of individual supporter effects on caller outcomes. This resource enables research in psychedelic epidemiology, evidence-based training design, and the investigation of what makes psychedelic psychological support effective.

Related

  1. From Evidence to Practice: A Systematic Review of Implementation of Psychedelic-Assisted Psychotherapy
    John D. Gault, Erin Almklov, Shirley Tang +3
    Psychedelic MedicinePeer-reviewedLicence not statedFull textPsychiatry & mental healthPMC
  2. HuRInterDB: A Database Exploring the Landscape of lncRNA-Protein Interactions.
    Qianwen Xie, Wenju Sun, Jian Yan
    Computational and structural biotechnology journalPeer-reviewedCC BYFull textOncologyEurope PMC
  3. Drug interactions in rheumatoid arthritis: a disparity between electronic database prediction and real-world co-prescription with different large language models.
    Tonson Lalitkanjanakul, Dhanesh Pitidhammabhorn, Natnicha Jakramonpreeya +3
    Therapeutic advances in drug safetyPeer-reviewedCC BY-NCFull textGeneral medicineEurope PMC
  4. A Multisource, Multilevel Contextual Database to Support Ending the HIV Epidemic Initiative: Protocol for Design, Construction, Harmonization, and Quality Assurance
    Nikita Rao, Lingling Zheng, Wyatt Deihl +4
    JMIR Research ProtocolsPeer-reviewedCC BY 4.0Full textInfectious diseasePMC
  5. Nutritional Management of Polyendocrine Metabolic Ovarian Syndrome: Current Evidence on Dietary Strategies, Supplementation, and Lifestyle Support
    Marek Murawski, Agata Góral, Marta Maria Miszczak +1
    NutrientsPeer-reviewedCC BYFull textNutritionEurope PMC
BibTeX
@article{schoeller2026fireside,
  title = {{The Fireside Database: Large-scale evidence from 25,419 psychedelic support interactions}},
  author = {Felix Schoeller and Marc Santolini and Dana Xiadani and Mickael Eskinazi and Ashwin Murali and David Esselman and Wyatt Houtz and Wesley Bellanca and Joshua White},
  journal = {Science Advances},
  year = {2026},
  month = oct,
  doi = {10.1126/sciadv.aeg4737},
  url = {https://www.science.org/doi/abs/10.1126/sciadv.aeg4737},
  note = {CC BY-NC},
}
RIS
TY  - JOUR
TI  - The Fireside Database: Large-scale evidence from 25,419 psychedelic support interactions
AU  - Felix Schoeller
AU  - Marc Santolini
AU  - Dana Xiadani
AU  - Mickael Eskinazi
AU  - Ashwin Murali
AU  - David Esselman
AU  - Wyatt Houtz
AU  - Wesley Bellanca
AU  - Joshua White
PY  - 2026
DA  - 2026/10/30
JO  - Science Advances
DO  - 10.1126/sciadv.aeg4737
UR  - https://www.science.org/doi/abs/10.1126/sciadv.aeg4737
AB  - Most psychedelic experiences occur outside clinical settings, yet as policy frameworks rapidly expand to accommodate nonclinical use, no systematic data exist on who seeks psychedelic support, under what circumstances, or what makes that support effective. We present the Fireside Database, a US-based dataset comprising 25,419 peer support interactions conducted by 220 trained volunteers at Fireside Project's Psychedelic Support Line between April 2021 and February 2026. The released resource integrates structured interaction logs with volunteer-coded metadata and 2777 caller satisfaction surveys across five outcome dimensions. Psilocybin was the most commonly reported substance (59.9% of coded interactions), while cannabis produced the highest distress rate (47.2%). The nested data structure-with 50 supporters each completing ≥10 surveyed interactions-supports multilevel modeling of individual supporter effects on caller outcomes. This resource enables research in psychedelic epidemiology, evidence-based training design, and the investigation of what makes psychedelic psychological support effective.
SN  - 2375-2548
ER  -