Risk factors of caustic agent ingestion in a single center in Tehran.
- 1Pediatric Surgery Research Center, Research Institute for Children's Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
- 2Pediatric Gastrointestinal Research Center, Research Institute for Children's Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abstract
Background
Caustic ingestion remains a preventable but persistent cause of morbidity in children. This study aimed to identify risk factors associated with caustic substance ingestion in children.Methods
In this case-control study, 122 children aged <18 years were included. Cases comprised 54 children with caustic ingestion referred to Mofid Children's Hospital between 2016 and 2022, while 68 randomly selected hospitalized children without esophageal burns served as controls. Sociodemographic and behavioral characteristics were collected using a validated checklist and compared between groups.Results
Most cases were aged 1-5 years (40, 74.1%) and involved girls (22, 40.7%). Acid ingestion accounted for 31 cases (57.4%). Domestic problems were significantly more common among cases than controls (40.7% vs. 22.1%; P=0.029; OR=2.429, 95% CI: 1.103-5.350). Higher family income (>30 million IRR) was associated with lower odds of caustic ingestion (OR=0.412, 95% CI: 0.187-0.907). Most incidents occurred at home (72.2%) and while parents were present (90.7%). Child-resistant safety caps were absent in 92.6% of cases, and 61.1% involved substances stored in their original containers; these variables were not compared with controls.Conclusion
Domestic problems and lower family income were significant risk factors for pediatric caustic ingestion. Socioeconomic support, parental education, safer household storage, and stronger safety regulations may help prevent these potentially avoidable injuries.
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BibTeX
@article{tabari2026risk,
title = {{Risk factors of caustic agent ingestion in a single center in Tehran.}},
author = {Nasibeh Khaleghnejad Tabari and Rosminasadat Moulaie and Mehdi Sarafi and Gholamreza Ebrahimisaraj and Amirhossein Hosseini and Arameh Abbasian and Ahmad Khaleghnejad Tabari},
journal = {Caspian journal of internal medicine},
year = {2026},
month = sep,
doi = {10.22088/cjim.17.3.653},
url = {https://europepmc.org/article/MED/42924366},
note = {CC BY-NC},
}
RIS
TY - JOUR
TI - Risk factors of caustic agent ingestion in a single center in Tehran.
AU - Nasibeh Khaleghnejad Tabari
AU - Rosminasadat Moulaie
AU - Mehdi Sarafi
AU - Gholamreza Ebrahimisaraj
AU - Amirhossein Hosseini
AU - Arameh Abbasian
AU - Ahmad Khaleghnejad Tabari
PY - 2026
DA - 2026/09/01
JO - Caspian journal of internal medicine
DO - 10.22088/cjim.17.3.653
UR - https://europepmc.org/article/MED/42924366
AB - Background Caustic ingestion remains a preventable but persistent cause of morbidity in children. This study aimed to identify risk factors associated with caustic substance ingestion in children.Methods In this case-control study, 122 children aged <18 years were included. Cases comprised 54 children with caustic ingestion referred to Mofid Children's Hospital between 2016 and 2022, while 68 randomly selected hospitalized children without esophageal burns served as controls. Sociodemographic and behavioral characteristics were collected using a validated checklist and compared between groups.Results Most cases were aged 1-5 years (40, 74.1%) and involved girls (22, 40.7%). Acid ingestion accounted for 31 cases (57.4%). Domestic problems were significantly more common among cases than controls (40.7% vs. 22.1%; P=0.029; OR=2.429, 95% CI: 1.103-5.350). Higher family income (>30 million IRR) was associated with lower odds of caustic ingestion (OR=0.412, 95% CI: 0.187-0.907). Most incidents occurred at home (72.2%) and while parents were present (90.7%). Child-resistant safety caps were absent in 92.6% of cases, and 61.1% involved substances stored in their original containers; these variables were not compared with controls.Conclusion Domestic problems and lower family income were significant risk factors for pediatric caustic ingestion. Socioeconomic support, parental education, safer household storage, and stronger safety regulations may help prevent these potentially avoidable injuries.
SN - 2008-6164
SN - 2008-6172
ER -