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Peer-reviewedCC BYJACC. Case reports

Transcatheter Closure of Apical Septal Rupture With Third Cavity Formation After Surgical Repair.

7 affiliations
  1. 1Department of Internal Medicine, PNS Shifa Hospital, Karachi, Pakistan.
  2. 2Department of Internal Medicine, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.
  3. 3Department of Pediatric Cardiology, PNS Shifa Hospital Karachi, Pakistan.
  4. 4Department of Internal Medicine, Jinnah Sindh Medical University, Karachi, Pakistan.
  5. 5Peshawar Medical College, Peshawar, Pakistan.
  6. 6Internal Medicine, Wright State University, Dayton, Ohio, USA.
  7. 7Texas Tech University, Texas, USA; West Virginia University, Camden Clark Medical Center, Parkersburg, West Virginia, USA; Interventional and Endovascular Cardiologist, Appalachian Regional Hospital, Beckley, West Virginia, USA. Electronic address: [email protected].

Abstract

Background

Apical septal rupture following surgical closure of a ventricular septal defect is a rare but life-threatening complication. Reoperation in such cases may be high risk, making transcatheter closure a viable and less invasive alternative.Case summary

We report an 8-month-old male infant who presented with cardiac failure with Ross class-III and severe respiratory distress. Clinical examination and imaging revealed an apical septal tear with formation of a third cavity extending toward the right ventricle and compromising right ventricular and left ventricular function. The patient underwent successful percutaneous device closure of the defect with complete recovery and no complications.Discussion

This case highlights the safety and efficacy of transcatheter closure in complex postsurgical ventricular septal defects. The minimally invasive nature of this approach makes it preferable in high-risk surgical candidates. Further studies are warranted to standardize outcomes for such interventions.Take-home message

Transcatheter closure is a safe, effective alternative in postsurgical congenital heart defects where reoperation poses a significant risk.

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BibTeX
@article{anwar2026transcatheter,
  title = {{Transcatheter Closure of Apical Septal Rupture With Third Cavity Formation After Surgical Repair.}},
  author = {Saqlain Anwar and Muhammad Ammar Nadeem and Hritvik Jain and Nadeem Sadiq and Areeba Shahid and Aizaz Anwar Khalid and Abhishek Kumar and Yasar Sattar},
  journal = {JACC. Case reports},
  year = {2026},
  month = oct,
  doi = {10.1016/j.jaccas.2026.110217},
  url = {https://europepmc.org/article/MED/42847570},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Transcatheter Closure of Apical Septal Rupture With Third Cavity Formation After Surgical Repair.
AU  - Saqlain Anwar
AU  - Muhammad Ammar Nadeem
AU  - Hritvik Jain
AU  - Nadeem Sadiq
AU  - Areeba Shahid
AU  - Aizaz Anwar Khalid
AU  - Abhishek Kumar
AU  - Yasar Sattar
PY  - 2026
DA  - 2026/10/01
JO  - JACC. Case reports
DO  - 10.1016/j.jaccas.2026.110217
UR  - https://europepmc.org/article/MED/42847570
AB  - Background  Apical septal rupture following surgical closure of a ventricular septal defect is a rare but life-threatening complication. Reoperation in such cases may be high risk, making transcatheter closure a viable and less invasive alternative.Case summary  We report an 8-month-old male infant who presented with cardiac failure with Ross class-III and severe respiratory distress. Clinical examination and imaging revealed an apical septal tear with formation of a third cavity extending toward the right ventricle and compromising right ventricular and left ventricular function. The patient underwent successful percutaneous device closure of the defect with complete recovery and no complications.Discussion  This case highlights the safety and efficacy of transcatheter closure in complex postsurgical ventricular septal defects. The minimally invasive nature of this approach makes it preferable in high-risk surgical candidates. Further studies are warranted to standardize outcomes for such interventions.Take-home message  Transcatheter closure is a safe, effective alternative in postsurgical congenital heart defects where reoperation poses a significant risk.
SN  - 2666-0849
ER  -