Project Psyche: reference genomes for all Lepidoptera in Europe
Abstract
Project Psyche is a transnational initiative to generate and study chromosome-level reference genomes of all ~11 000 species of Lepidoptera (butterflies and moths) found in Europe. Here, we describe the decentralised network of collection and sequencing hubs that has enabled rapid progress, the standardised protocols for sampling and sequencing, and the collaborative framework for data analysis. With over 1000 species already sequenced, Lepidoptera are at the forefront of biodiversity genomics with the most reference genomes of any eukaryotic order. The completed pan-European catalogue of openly accessible lepidopteran genomes will transform our understanding of evolution and ecology, inform conservation, and foster advances in management of pests and invasive species. We highlight research areas that will benefit from this large-scale genome dataset.
Related
- The Vertebrate Genomes Project Phase I: A global reference genome resource
- The complete mitochondrial genomes of Colias lada and Colias wanda (Lepidoptera: Pieridae: Coliadinae) and their phylogenetic analyses
- Phenological divergence between flowering plants and flower-visiting Lepidoptera under climate change across Europe
- Beyond single-trait analysis: ancient genomes reveal coordinated evolution of dietary endophenotypes in Holocene Europe
- The 100 Diatom Genomes Project
BibTeX
@article{wright2026project,
title = {{Project Psyche: reference genomes for all Lepidoptera in Europe}},
author = {Charlotte Wright and Niklas Wahlberg and Roger Vila and Marko Mutanen and Pável Matos-Maraví and Kay Lucek and Irena Kleckova and Leonardo Dapporto and Vlad Dincă and Claudia Bruschini and Christopher Wheat and Marta Vila and Laura Torrado-Blanco and Valentina Todisco and Michal Rindos and Petr Nguyen and Peter Mulhair and Stefaniya Kamenova and Marcus Hicks and Marianne Espeland and Ines Drinnenberg and Mónica Doblas-Bajo and Richard Bailey and Mark Blaxter and Joana Meier and Giada Zucco and Milica Zlatkovic and Marcin Wiorek and Martin Wiemers and Claudia Weber and Pavel Vrba and Vladimir Visacki and Jose Vicente Pérez Santa Rita and Mikko Vallinmäki and Başak Ulaşlı and Eric Toro-Delgado and Gerhard Thallinger and Alena Suchackova Bartonova and Jenny Stewart and Clara Spilker and Loukia Spilani and Dominik Schmitz and Benjamin Schattanek-Wiesmar and Petra Schattanek-Wiesmair and Stefano Scalercio and Gábor Sramkó Sramkó and Dejan Stojanovic and Cibele Sotero-Caio and Jadranka Rota and Mar Repullés and Łukasz Przybyłowicz and Pavel Potocký and Jaakko Pohjoismäki and Erki Õunap and Antonio Ortiz and Rayner Nunez and Vazrick Nazari and Ana Nahirnić-Beshkova and Tatiana Moreira and Marco Meyer},
journal = {Trends in Ecology \& Evolution},
year = {2026},
month = oct,
doi = {10.1016/j.tree.2025.10.007},
url = {https://hal.science/hal-05782922v1},
note = {CC BY},
}
RIS
TY - JOUR
TI - Project Psyche: reference genomes for all Lepidoptera in Europe
AU - Charlotte Wright
AU - Niklas Wahlberg
AU - Roger Vila
AU - Marko Mutanen
AU - Pável Matos-Maraví
AU - Kay Lucek
AU - Irena Kleckova
AU - Leonardo Dapporto
AU - Vlad Dincă
AU - Claudia Bruschini
AU - Christopher Wheat
AU - Marta Vila
AU - Laura Torrado-Blanco
AU - Valentina Todisco
AU - Michal Rindos
AU - Petr Nguyen
AU - Peter Mulhair
AU - Stefaniya Kamenova
AU - Marcus Hicks
AU - Marianne Espeland
AU - Ines Drinnenberg
AU - Mónica Doblas-Bajo
AU - Richard Bailey
AU - Mark Blaxter
AU - Joana Meier
AU - Giada Zucco
AU - Milica Zlatkovic
AU - Marcin Wiorek
AU - Martin Wiemers
AU - Claudia Weber
AU - Pavel Vrba
AU - Vladimir Visacki
AU - Jose Vicente Pérez Santa Rita
AU - Mikko Vallinmäki
AU - Başak Ulaşlı
AU - Eric Toro-Delgado
AU - Gerhard Thallinger
AU - Alena Suchackova Bartonova
AU - Jenny Stewart
AU - Clara Spilker
AU - Loukia Spilani
AU - Dominik Schmitz
AU - Benjamin Schattanek-Wiesmar
AU - Petra Schattanek-Wiesmair
AU - Stefano Scalercio
AU - Gábor Sramkó Sramkó
AU - Dejan Stojanovic
AU - Cibele Sotero-Caio
AU - Jadranka Rota
AU - Mar Repullés
AU - Łukasz Przybyłowicz
AU - Pavel Potocký
AU - Jaakko Pohjoismäki
AU - Erki Õunap
AU - Antonio Ortiz
AU - Rayner Nunez
AU - Vazrick Nazari
AU - Ana Nahirnić-Beshkova
AU - Tatiana Moreira
AU - Marco Meyer
PY - 2026
DA - 2026/10/07
JO - Trends in Ecology & Evolution
DO - 10.1016/j.tree.2025.10.007
UR - https://hal.science/hal-05782922v1
AB - Project Psyche is a transnational initiative to generate and study chromosome-level reference genomes of all ~11 000 species of Lepidoptera (butterflies and moths) found in Europe. Here, we describe the decentralised network of collection and sequencing hubs that has enabled rapid progress, the standardised protocols for sampling and sequencing, and the collaborative framework for data analysis. With over 1000 species already sequenced, Lepidoptera are at the forefront of biodiversity genomics with the most reference genomes of any eukaryotic order. The completed pan-European catalogue of openly accessible lepidopteran genomes will transform our understanding of evolution and ecology, inform conservation, and foster advances in management of pests and invasive species. We highlight research areas that will benefit from this large-scale genome dataset.
SN - 0169-5347
SN - 1872-8383
ER -