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Peer-reviewedCC BYClinical and translational allergy

A Current Evidence Review From the Italian Society of Pediatric Allergology and Immunology (SIAIP) on Practical Management of Allergic Rhinitis in Children and Adolescents.

7 affiliations
  1. 1Department of Medicine and Health Sciences, University of Molise, Campobasso, Italy.
  2. 2Pediatric Unit, Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, Pavia, Italy.
  3. 3Pediatrics, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
  4. 4Department of Woman and Child and General and Specialized Surgery, University of Campania Luigi Vanvitelli, Naples, Italy.
  5. 5Unit of Pediatrics, Department of Human Pathology in Adult and Developmental Age "Gaetano Barresi", University of Messina, Messina, Italy.
  6. 6Allergy Center, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
  7. 7Pediatric Department, La Sapienza University, Rome, Italy.

Abstract

Allergic rhinitis (AR) is highly prevalent in children and adolescents and impairs quality of life, sleep, and school performance, while also worsening asthma control. The last EAACI position paper on pediatric AR was published in 2013. Significant scientific advancements, including the new ARIA 2026 guidelines, necessitate an updated national framework. This Italian Society of Pediatric Allergology and Immunology (SIAIP) document aims to provide an evidence-based age-specific framework for the diagnosis, classification, and practical management of AR in children and adolescents, while addressing the limitations of existing less granular guidelines. A dedicated SIAIP experts' board reviewed current scientific literature, integrated updated epidemiological data, revised classifications, and emerging evidence on allergen immunotherapy. It incorporates the ARIA 2026 guidelines and adapts them to the clinical challenges and age-specific considerations relevant to pediatric practice. The board of qualified experts and a panel of multidisciplinary clinicians discussed and approved the document. This document covers the epidemiology, pathophysiology, and diagnosis of AR in children and adolescents. It provides detailed stepwise pharmacologic recommendations and discusses the role of allergen immunotherapy (AIT), taking age-specific factors and complementary therapies into account. Evidence-based statements and practical management algorithms aim to optimize diagnostic pathways and therapeutic interventions. This SIAIP document offers clinically actionable guidance for healthcare professionals. It emphasizes early diagnosis, stepwise treatment strategies, and the disease-modifying role of AIT, aiming to enhance diagnostic accuracy, streamline management, and ultimately improve the long-term health and well-being of affected children and adolescents.

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BibTeX
@article{ciprandi2026current,
  title = {{A Current Evidence Review From the Italian Society of Pediatric Allergology and Immunology (SIAIP) on Practical Management of Allergic Rhinitis in Children and Adolescents.}},
  author = {Giorgio Ciprandi and Amelia Licari and Cristiana Indolfi and Sara Manti and Michele Miraglia Del Giudice and Maria Angela Tosca and Anna Maria Zicari and Gianluigi Marseglia},
  journal = {Clinical and translational allergy},
  year = {2026},
  month = nov,
  doi = {10.1002/clt2.70218},
  url = {https://europepmc.org/article/MED/42998301},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - A Current Evidence Review From the Italian Society of Pediatric Allergology and Immunology (SIAIP) on Practical Management of Allergic Rhinitis in Children and Adolescents.
AU  - Giorgio Ciprandi
AU  - Amelia Licari
AU  - Cristiana Indolfi
AU  - Sara Manti
AU  - Michele Miraglia Del Giudice
AU  - Maria Angela Tosca
AU  - Anna Maria Zicari
AU  - Gianluigi Marseglia
PY  - 2026
DA  - 2026/11/01
JO  - Clinical and translational allergy
DO  - 10.1002/clt2.70218
UR  - https://europepmc.org/article/MED/42998301
AB  - Allergic rhinitis (AR) is highly prevalent in children and adolescents and impairs quality of life, sleep, and school performance, while also worsening asthma control. The last EAACI position paper on pediatric AR was published in 2013. Significant scientific advancements, including the new ARIA 2026 guidelines, necessitate an updated national framework. This Italian Society of Pediatric Allergology and Immunology (SIAIP) document aims to provide an evidence-based age-specific framework for the diagnosis, classification, and practical management of AR in children and adolescents, while addressing the limitations of existing less granular guidelines. A dedicated SIAIP experts' board reviewed current scientific literature, integrated updated epidemiological data, revised classifications, and emerging evidence on allergen immunotherapy. It incorporates the ARIA 2026 guidelines and adapts them to the clinical challenges and age-specific considerations relevant to pediatric practice. The board of qualified experts and a panel of multidisciplinary clinicians discussed and approved the document. This document covers the epidemiology, pathophysiology, and diagnosis of AR in children and adolescents. It provides detailed stepwise pharmacologic recommendations and discusses the role of allergen immunotherapy (AIT), taking age-specific factors and complementary therapies into account. Evidence-based statements and practical management algorithms aim to optimize diagnostic pathways and therapeutic interventions. This SIAIP document offers clinically actionable guidance for healthcare professionals. It emphasizes early diagnosis, stepwise treatment strategies, and the disease-modifying role of AIT, aiming to enhance diagnostic accuracy, streamline management, and ultimately improve the long-term health and well-being of affected children and adolescents.
SN  - 2045-7022
ER  -