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Peer-reviewedCC BY-NC 4.0Iranian Journal of Child Neurology

Status Epilepticus in Children: Clinical Features, Management, and Outcomes in a Single-Center Experience

  • Hamit Acer1
  • Mehmet Canpolat2
  • Hüseyin Per2
  • Hakan Gumus2
  • Basak Nur Akyildiz3
  • Sefer Kumandas2
  1. 1Pediatric Neurology, Department of Pediatrics, Denizli State Hospital, Denizli, TURKEY
  2. 2Department of Pediatrics, Division of Pediatric Neurology, Erciyes University, Faculty of Medicine, Kayseri, TURKEY
  3. 3Department of Pediatrics, Division of Pediatric Intensive Care, Erciyes University, Faculty of Medicine, Kayseri, TURKEY
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Abstract

Objectives:: The classification of status epilepticus (SE) has undergone several revisions, with the most recent update published by the International League Against Epilepsy (ILAE) in 2015. However, in seizures lasting longer than 10 minutes, there is still no consensus on optimal drug selection.

Materials and Methods:: This retrospective study reviewed the medical records of patients diagnosed with SE and followed in the Pediatric Intensive Care Unit, Pediatric Neurology, and Pediatric Emergency Unit at Erciyes University Faculty of Medicine.

Results:: A total of 64 patients were included. Sequential therapy with levetiracetam following phenytoin proved to be an effective treatment strategy prior to escalation to third-line agents. In our clinic, rapid MRI protocols, including axial T1, axial T2, sagittal T2, and diffusion-weighted sequences, were preferred for emergency neuroimaging. These rapid protocols were both practical and effective in the acute management of SE.

Conclusions:: Rapid brain MRI techniques are easy to apply and provide valuable diagnostic insights into the etiology of SE. Sequential administration of second-line drugs may reduce the side-effect profile and optimize seizure control in children with SE.

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Cite

BibTeXRIS
BibTeX
@article{acer2026status,
  title = {{Status Epilepticus in Children: Clinical Features, Management, and Outcomes in a Single-Center Experience}},
  author = {Hamit Acer and Mehmet Canpolat and Hüseyin Per and Hakan Gumus and Basak Nur Akyildiz and Sefer Kumandas},
  journal = {Iranian Journal of Child Neurology},
  year = {2026},
  month = sep,
  doi = {10.22037/ijcn.v20i4.50012},
  url = {https://doi.org/10.22037/ijcn.v20i4.50012},
  note = {CC BY-NC 4.0},
}
RIS
TY  - JOUR
TI  - Status Epilepticus in Children: Clinical Features, Management, and Outcomes in a Single-Center Experience
AU  - Hamit Acer
AU  - Mehmet Canpolat
AU  - Hüseyin Per
AU  - Hakan Gumus
AU  - Basak Nur Akyildiz
AU  - Sefer Kumandas
PY  - 2026
DA  - 2026/09/01
JO  - Iranian Journal of Child Neurology
DO  - 10.22037/ijcn.v20i4.50012
UR  - https://doi.org/10.22037/ijcn.v20i4.50012
AB  - Objectives:: The classification of status epilepticus (SE) has undergone several revisions, with the most recent update published by the International League Against Epilepsy (ILAE) in 2015. However, in seizures lasting longer than 10 minutes, there is still no consensus on optimal drug selection.  Materials and Methods:: This retrospective study reviewed the medical records of patients diagnosed with SE and followed in the Pediatric Intensive Care Unit, Pediatric Neurology, and Pediatric Emergency Unit at Erciyes University Faculty of Medicine.  Results:: A total of 64 patients were included. Sequential therapy with levetiracetam following phenytoin proved to be an effective treatment strategy prior to escalation to third-line agents. In our clinic, rapid MRI protocols, including axial T1, axial T2, sagittal T2, and diffusion-weighted sequences, were preferred for emergency neuroimaging. These rapid protocols were both practical and effective in the acute management of SE.  Conclusions:: Rapid brain MRI techniques are easy to apply and provide valuable diagnostic insights into the etiology of SE. Sequential administration of second-line drugs may reduce the side-effect profile and optimize seizure control in children with SE.
SN  - 1735-4668
SN  - 2008-0700
ER  -