Skip to content
DraconiticResearch
Search Sources API
197,768 studies31 sourcesUpdated 11 min ago
Peer-reviewedLicence not statedJournal of the American Heart Association

BPR‐30901649, An Angiotensinogen‐Targeting Small Interfering RNA, Achieves Ultra‐Durable Target Silencing and Sustained Blood Pressure Reduction Through 20 Weeks in Hypertensive Non‐Human Primates

  • Wen Liu1,2
  • Shuai Pei1
  • Jiaqi Lu1
  • Yi Chen1
  • Keke Zou1,2
  • Jiachuan Duan1
  • Chao Zang1,2
  • Xiwen Cheng2
  • Haoxi Huang1,2
  • Yu Chen1,2
  1. 1Chengdu Brilliant AcuRNA Biopharmaceutical Co., Ltd.
  2. 2Brilliant Pharmaceutical Co., Ltd.
Open at sourceDOICite

Related

  1. N-Acetylgalactosamine-Conjugated Small Interfering RNA Targeting Hepatic Angiotensinogen in Hypertension: A Phase I Clinical Trial With Randomized Part A and Open-Label Part B.
    Jianxiong Zhang, Jingxuan Wu, Que Liu +11
    JAMA cardiologyPeer-reviewedCC BY-NC-NDFull textCardiovascular medicineEurope PMC
  2. Lower circulating angiotensinogen levels across ACLD stages are associated with hepatic dysfunction and mortality
    Marlene Hintersteininger, Benedikt Silvester Hofer, Clemens Renhardt +12
    Hepatology communicationsPeer-reviewedCC BY-NC-NDFull textGeneral medicineEurope PMC
  3. Angiotensinogen as a molecular hub in interorgan communication.
    Jianan Zhou, Ximing Ye, Yuying Wang +4
    Journal of translational medicinePeer-reviewedCC BY-NC-NDFull textCardiovascular medicineEurope PMCPMC
  4. A PD‐L1 Nanobody‐Engineered Synthetic RNA Virus Enhances Hepatocellular Carcinoma Immunotherapy by Interfering PCSK9 and Upregulating MHC‐I
    Chuyu Huang, Yun Ye, Yi Guo +7
    ExplorationPeer-reviewedCC BY 4.0Full textOncologyPMC
  5. RNA-Based Therapies for Lipoprotein(a) Reduction: Antisense Oligonucleotides, Small Interfering RNAs, and Emerging Platforms.
    Vibhu Parcha, Vera A Bittner
    Current atherosclerosis reportsPeer-reviewedCC BYFull textSurgery & anaesthesiaEurope PMC

Cite

BibTeXRIS
BibTeX
@article{liu2026bpr30901649,
  title = {{BPR‐30901649, An Angiotensinogen‐Targeting Small Interfering RNA, Achieves Ultra‐Durable Target Silencing and Sustained Blood Pressure Reduction Through 20 Weeks in Hypertensive Non‐Human Primates}},
  author = {Wen Liu and Shuai Pei and Jiaqi Lu and Yi Chen and Keke Zou and Jiachuan Duan and Chao Zang and Xiwen Cheng and Haoxi Huang and Yu Chen},
  journal = {Journal of the American Heart Association},
  year = {2026},
  month = nov,
  doi = {10.1161/jaha.126.055499},
  url = {https://www.ahajournals.org/doi/10.1161/JAHA.126.055499},
}
RIS
TY  - JOUR
TI  - BPR‐30901649, An Angiotensinogen‐Targeting Small Interfering RNA, Achieves Ultra‐Durable Target Silencing and Sustained Blood Pressure Reduction Through 20 Weeks in Hypertensive Non‐Human Primates
AU  - Wen Liu
AU  - Shuai Pei
AU  - Jiaqi Lu
AU  - Yi Chen
AU  - Keke Zou
AU  - Jiachuan Duan
AU  - Chao Zang
AU  - Xiwen Cheng
AU  - Haoxi Huang
AU  - Yu Chen
PY  - 2026
DA  - 2026/11/06
JO  - Journal of the American Heart Association
DO  - 10.1161/jaha.126.055499
UR  - https://www.ahajournals.org/doi/10.1161/JAHA.126.055499
SN  - 2047-9980
ER  -